CAS 338738-57-1

6-methoxy-N-(4-methoxyphenyl)quinazolin-4-amine hydrochloride

Description:

6-Methoxy-N-(4-methoxyphenyl)quinazolin-4-amine hydrochloride is a chemical compound characterized by its quinazoline core structure, which is a bicyclic compound containing two nitrogen atoms in the ring. This substance features methoxy groups that enhance its solubility and may influence its biological activity. The presence of the hydrochloride salt form indicates that it is a hydrochloride salt, which typically improves the stability and solubility of the compound in aqueous solutions. This compound may exhibit potential pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its specific interactions and mechanisms of action would depend on its molecular structure and the functional groups present. As with many quinazoline derivatives, it may be investigated for its role in various biological pathways, including potential anti-cancer or anti-inflammatory activities. Safety and handling precautions should be observed, as with all chemical substances, particularly in laboratory settings.

Formula: C₁₆H₁₆ClN₃O₂

InChI: InChI=1/C16H15N3O2.ClH/c1-20-12-5-3-11(4-6-12)19-16-14-9-13(21-2)7-8-15(14)17-10-18-16;/h3-10H,1-2H3,(H,17,18,19);1H

SMILES: COc1ccc(cc1)Nc1c2cc(ccc2ncn1)OC.Cl

Synonyms:

• (4-methoxy-phenyl)-(6-methoxy-quinazolin-4-yl)-amine HCl
• 4-Quinazolinamine, 6-methoxy-N-(4-methoxyphenyl)-, hydrochloride (1:1)
• 6-Methoxy-N-(4-methoxyphenyl)quinazolin-4-amine hydrochloride (1:1)

Ly 456236 hydrochloride

CAS: 338738-57-1

Allosteric modulation of the dopamine receptor is a novel therapeutic approach to treat neurodegenerative disorders such as Parkinson's disease. Ly 456236 hydrochloride (LY456236) is an allosteric modulator that can regulate the activity of the D2 dopamine receptor by binding to an allosteric site. It has been shown to be neuroprotective in animal models and has clinical properties in humans. LY456236 does not bind to the glutamate or nicotinic acetylcholine receptors and does not cause locomotor activity or cholinergic symptoms. LY456236 also shows antidepressant effects, which may be due to its ability to regulate serotonin neurotransmission.

Formula: C₁₆H₁₆ClN₃O₂

Purity: Min. 95%

Molecular weight: 317.77 g/mol

Ref: 3D-NNA73857