CAS 3392-07-2
:N-(tert-Butyloxycarbonyl)glycine N-hydroxysuccinimide ester
Description:
N-(tert-Butyloxycarbonyl)glycine N-hydroxysuccinimide ester, commonly referred to as Boc-Gly-NHS, is a chemical compound used primarily in peptide synthesis and bioconjugation. It features a tert-butyloxycarbonyl (Boc) protecting group on the amino group of glycine, which provides stability and protects the amine during reactions. The N-hydroxysuccinimide (NHS) ester moiety is highly reactive towards nucleophiles, making it an effective coupling agent for forming amide bonds with amino acids or peptides. This compound is typically a white to off-white solid and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). Its reactivity and stability make it valuable in various applications, including the synthesis of peptide libraries and the modification of biomolecules. Additionally, the Boc group can be easily removed under mild acidic conditions, allowing for the subsequent deprotection of the amino group when needed. Overall, Boc-Gly-NHS is an important reagent in the field of organic and medicinal chemistry.
Formula:C11H16N2O6
InChI:InChI=1S/C11H16N2O6/c1-11(2,3)18-10(17)12-6-9(16)19-13-7(14)4-5-8(13)15/h4-6H2,1-3H3,(H,12,17)
InChI key:InChIKey=LJCWRJYVPJJTMB-UHFFFAOYSA-N
SMILES:O(C(CNC(OC(C)(C)C)=O)=O)N1C(=O)CCC1=O
Synonyms:- 2,5-Dioxopyrrolidin-1-yl 2-(tert-butoxycarbonylamino)acetate
- 2,5-dioxopyrrolidin-1-yl N-(tert-butoxycarbonyl)glycinate
- Boc-Gly-OSu
- Carbamic acid, [2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-, 1,1-dimethylethyl ester
- Glycine, N-[(1,1-dimethylethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester
- N-(tert-Butyloxycarbonyl)glycine N-hydroxysuccinimide ester
- N-Boc-glycine N-hydroxysuccinimidyl ester
- N-Boc-glycine hydroxysuccinimide ester
- N-[[N-(tert-Butoxycarbonyl)glycyl]oxy]succinimide
- N-tert-Butoxycarbonylglycine N-hydroxysuccinimide ester
- NSC 164050
- Succinimide, N-[(N-carboxyglycyl)oxy]-, tert-butyl ester
- See more synonyms
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Found 7 products.
N-Boc-glycine N-succinimidyl ester, 98%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Formula:C11H16N2O6Purity:98%Molecular weight:272.26Boc-Gly-OSu
CAS:<p>Bachem ID: 4001333.</p>Formula:C11H16N2O6Purity:> 98%Color and Shape:White PowderMolecular weight:272.26N-(tert-Butyloxycarbonyl)glycine N-hydroxysuccinimide ester
CAS:Formula:C11H16N2O6Purity:95%Color and Shape:SolidMolecular weight:272.2545Boc-glycine N-hydroxysuccinimide ester
CAS:<p>This is a high quality reagent that is a useful intermediate in the synthesis of complex compounds. It is also a fine chemical and a useful scaffold for the synthesis of complex molecules. Boc-glycine N-hydroxysuccinimide ester has many applications in research chemistry, such as being used as an intermediate in the synthesis of other organic compounds. It can also be used as a building block for creating diverse compounds with different reactive groups. Boc-glycine N-hydroxysuccinimide ester is soluble in water, making it suitable for use in reactions involving water. This versatile building block can be used to create drugs, pesticides, and other chemicals.</p>Formula:C11H16N2O6Purity:Min. 95%Color and Shape:SolidMolecular weight:272.25 g/mol






