CAS 33956-61-5

Tetranactin

Description:

Tetranactin, with the CAS number 33956-61-5, is a chemical compound that belongs to the class of polyene antibiotics. It is primarily known for its antifungal properties, making it useful in the treatment of various fungal infections. Tetranactin exhibits a complex structure characterized by multiple conjugated double bonds, which contribute to its biological activity. The compound interacts with fungal cell membranes, disrupting their integrity and leading to cell death. It is typically administered in a clinical setting, and its efficacy is influenced by factors such as the specific fungal strain and the concentration used. As with many antibiotics, the potential for resistance development is a concern, necessitating careful use. Safety and toxicity profiles are essential considerations, and it is important to follow guidelines for its use to minimize adverse effects. Overall, tetranactin represents a significant tool in antifungal therapy, particularly in cases where other treatments may be ineffective.

Formula: C₄₄H₇₂O₁₂

InChI: InChI=1S/C44H72O12/c1-9-29-21-33-13-17-38(49-33)26(6)42(46)54-31(11-3)23-35-15-19-40(51-35)28(8)44(48)56-32(12-4)24-36-16-20-39(52-36)27(7)43(47)55-30(10-2)22-34-14-18-37(50-34)25(5)41(45)53-29/h25-40H,9-24H2,1-8H3

InChI key: InChIKey=NKNPHSJWQZXWIX-UHFFFAOYSA-N

SMILES: CC1C2OC(CC2)CC(CC)OC(=O)C(C)C3OC(CC3)CC(CC)OC(=O)C(C)C4OC(CC(CC)OC(=O)C(C)C5OC(CC(CC)OC1=O)CC5)CC4

Synonyms:

• (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-5,14,23,32-Tetraethyl-2,11,20,29-tetramethyl-4,13,22,31,37,38,39,40-octaoxapentacyclo[32.2.1.1^7,10.1^16,19.1^25,28]tetracontane-3,12,21,30-tetrone
• (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-5,14,23,32-Tetraethyl-2,11,20,29-tetramethyl-4,13,22,31,37,38,39,40-octaoxapentacyclo[32.2.1.1~7,10~.1~16,19~.1~25,28~]tetracontan-3,12,21,30-tetron
• 33956-61-5
• 4,13,22,31,37,38,39,40-Octaoxapentacyclo[32.2.1.1^7,10.1^16,19.1^25,28]tetracontane, nonactin deriv.
• 4,13,22,31,37,38,39,40-Octaoxapentacyclo[32.2.1.1^7,10.1^16,19.1^25,28]tetracontane-3,12,21,30-tetrone, 5,14,23,32-tetraethyl-2,11,20,29-tetramethyl-, (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-
• 4,13,22,31,37,38,39,40-Octaoxapentacyclo[32.2.1.1^7,10.1^16,19.1^25,28]tetracontane-3,12,21,30-tetrone, 5,14,23,32-tetraethyl-2,11,20,29-tetramethyl-, [1R-(1R*,2R*,5R*,7R*,10S*,11S*,14S*,16S*,19R*,20R*,23R*,25R*,28S*,29S*,32S*,34S*)]-
• Nonactin, 5,14,23,32-tetrademethyl-5,14,23,32-tetraethyl-
• Tetranactin
• (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-5,14,23,32-Tetraethyl-2,11,20,29-tetramethyl-4,13,22,31,37,38,39,40-octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone
• 4,13,22,31,37,38,39,40-Octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone, 5,14,23,32-tetraethyl-2,11,20,29-tetramethyl-, (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-
• 4,13,22,31,37,38,39,40-Octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane, nonactin deriv.

Tetranactin

CAS: 33956-61-5

Tetranactin: a macrotetrolide ionophore with antibacterial and insecticidal effects; inhibits Gram-positive bacteria and certain fungi.

Formula: C₄₄H₇₂O₁₂

Color and Shape: Solid

Molecular weight: 793.048

Ref: TM-T37052