CAS 34031-32-8
:Auranofin
Description:
Auranofin is a gold-containing compound primarily used in the treatment of rheumatoid arthritis. It belongs to the class of drugs known as gold salts, which have anti-inflammatory properties. The chemical formula for Auranofin is C20H17AuO9PS, indicating that it contains gold, sulfur, phosphorus, and several organic components. Auranofin functions by modulating the immune response and inhibiting the activity of certain enzymes involved in inflammation. It is typically administered orally and is known for its relatively low toxicity compared to other gold compounds. However, it can still cause side effects, including gastrointestinal disturbances and potential allergic reactions. The compound's mechanism of action involves the inhibition of macrophage activation and the modulation of cytokine production, contributing to its therapeutic effects. Auranofin has also garnered interest in research for its potential applications beyond arthritis, including its antiparasitic and anticancer properties. As with any medication, its use should be monitored by healthcare professionals to manage any adverse effects effectively.
Formula:C20H34AuO9PS
InChI:InChI=1/C6H15P.Au/c1-4-7(5-2)6-3;/h4-6H2,1-3H3;/q;+1
InChI key:InChIKey=AUJRCFUBUPVWSZ-XTZHGVARSA-M
SMILES:O(C(C)=O)[C@@H]1[C@@H](OC(C)=O)[C@H]([S-][Au+][P](CC)(CC)CC)O[C@H](COC(C)=O)[C@H]1OC(C)=O
Synonyms:- (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate
- 3,4,5-Triacetoxy-6-(Acetoxymethyl)Tetrahydropyran-2-Thiolate
- Aktil
- Auranofina
- Auranofine
- Crisinor
- Crisofin
- Gold Salt
- Gold(+1) Cation
- Gold, (1-thio-β-<span class="text-smallcaps">D</span>-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate
- Gold, (1-thio-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-
- Gold, (1-thio-β-D-glucopyranosato)(triethylphosphine)-, 2,3,4,6-tetraacetate
- Gold, (1-thio-β-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-
- Gold, [1-(thio-κS)-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-
- Gold, [1-(thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-
- Nsc 321521
- Phosphine, Triethyl-, Gold(1+) Salt (1:1)
- Ridaura
- Ridauran
- Skf 39162
- Skf 39162D
- Triethylphosphonium
- [(Tetra-O-acetyl-β-<span class="text-smallcaps">D</span>-glucopyranosyl)thio](triethylphosphine)gold
- [(Tetra-O-acetyl-β-D-glucopyranosyl)thio](triethylphosphine)gold
- [1-(Thio-κS)-β-<span class="text-smallcaps">D</span>-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold
- β-<span class="text-smallcaps">D</span>-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex
- β-D-Glucopyranose, 1-thio-, 2,3,4,6-tetraacetate, gold complex
- [1-(Thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold
- 3,4,5-Triacetyloxy-6-(acetyloxymethyl) oxane-2-thiolate triethylphosphanium
- gold,(1-thio-beta-d-glucopyranose2,3,4,6-tetraacetato-s)(triethylphosphine)
- Gold, [1-(thio-kS)-b-D-glucopyranose2,3,4,6-tetraacetato](triethylphosphine)-
- sk&f39162
- 2,3,4,6-tetra-o-acetyl-1-thio-beta-d-glucopyranosato-s(triethylphosphine)gol
- sk&f39162d
- (1-thio-beta-d-glucopyranosato)-(triethylphosphine)gold2,3,4,6-tetraacetate
- (1-Thio-β-D-glucopyranosato)(triethylphosphine)gold-2，3，4，6-tetraacetate
- gold,(1-thio-beta-d-glucopyranosato-s)(triethylphosphine)-,2,3,4,6-tetraaceta
- AURANOFIN
- sk&fd-39162
- Adtil
- Auranofin, >=98%
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Found 9 products.
(1-Thio-β-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate
CAS:Formula:C20H34AuO9PSPurity:98%Color and Shape:SolidMolecular weight:678.4839Ref: IN-DA00382F
1gTo inquire1mg52.00€10mg89.00€50mg168.00€100mg271.00€250mgTo inquire500mgTo inquireAuranofin
CAS:<p>Auranofin (SKF-39162), an antirheumatic, treats rheumatoid arthritis and eases joint pain and stiffness.</p>Formula:C20H34AuO9PSPurity:97% - 99.01%Color and Shape:White Crystalline Powder SolidMolecular weight:678.49((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(Acetoxymethyl)Tetrahydro-2H-Pyran-2-Thio)(Triethylphosphine)Gold
CAS:((2S,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(Acetoxymethyl)Tetrahydro-2H-Pyran-2-Thio)(Triethylphosphine)GoldPurity:98%Molecular weight:678.5g/molAuranofine
CAS:Formula:C20H34AuO9PSPurity:≥ 95.0%Color and Shape:White to off-white solidMolecular weight:678.48Auranofin
CAS:<p>Auranofin is a chrysotherapeutic agent which inhibits histamine release from human basophils. Auranofin is gold-containing salt extensively used in the treatment of rheumatoid arthritis. Auranofin has antimicrobial properties and inhibits the growth of Clostridium difficile more effectively than vancomycin and metronidazole. According to in vitro studies carried out in 2020, auranofin inhibits the replication of coronavirus SARS-CoV-2 and reduces inflammation in human cells.</p>Formula:C20H34AuO9PSColor and Shape:White Off-White PowderMolecular weight:678.49 g/molAuranofin-13C6
CAS:Controlled ProductFormula:C14C6H34AuO9PSColor and Shape:NeatMolecular weight:684.44Auranofin
CAS:Controlled Product<p>Applications Auranofin is a new oral gold-based antiarthritis drug. Auranofin inhibits various leukocyte activation pathways at multiple sites. Auranofin inhibits the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin is an efficient inducer of mitochondrial membrane permeability transition pore in the presence of calcium ions related to its inhibition of mitochondrial thioredoxin reductase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kizu, R., et al.: Chem. Pharm. Bull., 41, 1261 (1993), Itokazu, M., et al.: Clin. Ther., 17, 60 (1995), Kean, W.F., et al.: Br. J. Rheumatol., 36, 560 (1997),<br></p>Formula:C20H34AuO9PSColor and Shape:NeatMolecular weight:678.48
