CAS 34041-84-4

Isoquinoline,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-7-methoxy-2-methyl-, hydrochloride(1:1)

Description:

Isoquinoline, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-7-methoxy-2-methyl-, hydrochloride (1:1), with CAS number 34041-84-4, is a chemical compound that belongs to the isoquinoline class of heterocyclic compounds. It features a tetrahydroisoquinoline structure, which is characterized by a fused bicyclic system containing nitrogen. The presence of the 3,4-dichlorophenyl group indicates that it has significant substituents that can influence its chemical reactivity and biological activity. The methoxy and methyl groups contribute to its overall hydrophobic character, potentially affecting its solubility and interaction with biological systems. As a hydrochloride salt, it is typically more stable and soluble in aqueous solutions, which is advantageous for pharmaceutical applications. This compound may exhibit various pharmacological properties, making it of interest in medicinal chemistry. However, specific biological activities and safety profiles would require further investigation through empirical studies.

Formula: C₁₇H₁₇Cl₂NOClH

Synonyms:

• Isoquinoline,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-7-methoxy-2-methyl-, hydrochloride(8CI,9CI)
• Isoquinoline,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-7-methoxy-2-methyl-, hydrochloride, (?à)- (8CI)

Diclofensine Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 34041-84-4

Color and Shape: Single Solution

Ref: 61-AMP1275.18-01

Diclofensine hydrochloride

CAS: 34041-84-4

Diclofensine hydrochloride (Ro 8-4650 hydrochloride) 是一种高效单胺再摄取抑制剂，在大鼠脑突触体中能够阻断多巴胺 (IC50=0.74 nM)、去甲肾上腺素 (IC50=2.3 nM) 和 5-羟色胺 (IC50=3.7 nM)。

Formula: C₁₇H₁₈Cl₃NO

Purity: 98.86% - 99.93%

Color and Shape: Solid

Molecular weight: 358.69

Ref: TM-T7745

Diclofensine Hydrochloride

Controlled Product

CAS: 34041-84-4

Applications Diclofensine is a stimulant; inhibits reuptake of dopamine and noradrenaline, is an effective antidepressant. Diclofensine exhibits significant addictive properties.
References Supersaxo, A., et al.: Pharm. Res., 8, 1286 (1991), Nakachi, N., et al.: Eur. J. Pharmacol., 281, 195 (1995), Chankvetadze, B., et al.: J. Pharm. Biomed. Anal., 27, 467 (2001),

Formula: C₁₇H₁₇Cl₂NO·ClH

Color and Shape: White

Molecular weight: 358.69

Ref: TR-D436580

Diclofensine hydrochloride

Controlled Product

CAS: 34041-84-4

Diclofensine hydrochloride is a synthetic cannabinoid that has been shown to produce amphetamine-like locomotor stimulation in rats. It is also an inhibitor of the uptake of dopamine and norepinephrine in the rat striatum, and it inhibits the mitochondrial membrane potential in cells from the rat striatum. Diclofensine is a potent agonist at human dopamine D2 receptors, with low potency for other neurotransmitter receptors. The drug binds to the dopamine transporter and blocks its activity, leading to increased levels of synaptic dopamine. This increase in synaptic dopamine may be responsible for diclofensine's effect on locomotor activity.

Formula: C₁₇H₁₈Cl₃NO

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 358.69 g/mol

Ref: 3D-FD21716

Diclofensine Hydrochloride

CAS: 34041-84-4

Color and Shape: Neat

Ref: 61-FOR1275.18