CAS 34042-85-8

Sudoxicam

Description:

Sudoxicam, identified by its CAS number 34042-85-8, is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the oxicam class of compounds. It is primarily used for its analgesic and anti-inflammatory properties, making it effective in the treatment of conditions such as arthritis and other inflammatory disorders. Sudoxicam functions by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which play a crucial role in the biosynthesis of prostaglandins, mediators of inflammation and pain. The compound is characterized by its relatively long half-life, allowing for less frequent dosing compared to some other NSAIDs. Additionally, Sudoxicam exhibits a favorable gastrointestinal safety profile, which is an important consideration in the long-term management of chronic pain. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, contribute to its therapeutic efficacy and safety. As with all medications, potential side effects and contraindications should be considered, and it is essential to use Sudoxicam under the guidance of a healthcare professional.

Formula: C₁₃H₁₁N₃O₄S₂

InChI: InChI=1/C13H11N3O4S2/c1-16-10(12(18)15-13-14-6-7-21-13)11(17)8-4-2-3-5-9(8)22(16,19)20/h2-7,17H,1H3,(H,14,15,18)

InChI key: InChIKey=SYCHUQUJURZQMO-UHFFFAOYSA-N

SMILES: OC=1C=2C(S(=O)(=O)N(C)C1C(NC3=NC=CS3)=O)=CC=CC2

Synonyms:

• (3Z)-3-[hydroxy(1,3-thiazol-2-ylamino)methylidene]-2-methyl-2,3-dihydro-4H-1,2-benzothiazin-4-one 1,1-dioxide
• 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-thiazolyl-, 1,1-dioxide
• 4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
• 4-hydroxy-2-methyl-N-(1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
• Cp 15973
• N-(2-Thiazolyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
• NSC 615046
• Normeloxicam
• Sudoxicam
• 4-Hydroxy-2-methyl-3-(2-thiazolylcarbamoyl)-2H-1,2-benzothiazine 1,1-dioxide
• 4-Hydroxy-2-methyl-N-(thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

Sudoxicam

CAS: 34042-85-8

Sudoxicam

Purity: ≥98%

Molecular weight: 337.37g/mol

Ref: 54-BUP09835

Sudoxicam

Controlled Product

CAS: 34042-85-8

Applications Sudoxicam and Meloxicam are nonsteroidal anti-inflammatory drugs (NSAIDs) from the enol-carboxamide class.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wiseman, E., et al.: Biochem. Pharmacol., 21, 2323 (1972), Schmid, J., et al.: Drug Metab. Dispos., 23, 1206 (1995), Marnett, L., et al.: J. Biol. Chem., 274, 22903 (1999), Ji, T., et al.: Chem. Res. Toxicol., 20, 701 (2007),

Formula: C₁₃H₁₁N₃O₄S₂

Color and Shape: Neat

Molecular weight: 337.37

Ref: TR-S688950

Sudoxicam

CAS: 34042-85-8

Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema

Formula: C₁₃H₁₁N₃O₄S₂

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 337.37

Ref: TM-T16950