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CAS 34079-31-7

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Z-Pro-NH2

Description:
Z-Pro-NH2, also known as Z-Proline amide, is a chemical compound characterized by its structure, which includes a proline amino acid derivative with a protective Z (benzyloxycarbonyl) group. This compound is primarily used in peptide synthesis and as an intermediate in the production of various pharmaceuticals. The Z group serves to protect the amino group during chemical reactions, allowing for selective modifications. Z-Pro-NH2 is typically a white to off-white solid and is soluble in polar solvents such as water and methanol, making it suitable for various biochemical applications. Its stability and reactivity are influenced by the presence of the amide functional group, which can participate in further reactions, including coupling with other amino acids to form peptides. As with many chemical substances, handling Z-Pro-NH2 requires standard safety precautions, including the use of personal protective equipment, due to potential irritant properties. Overall, Z-Pro-NH2 is a valuable compound in organic synthesis and biochemistry.
Formula:C13H16N2O3
InChI:InChI=1/C13H16N2O3/c14-12(16)11-7-4-8-15(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H2,14,16)/t11-/m0/s1
SMILES:c1ccc(cc1)COC(=O)N1CCC[C@H]1C(=N)O
Synonyms:
  • Z-L-proline amide
  • N-Benzyloxycarbonyl-L-Prolinamide
  • benzyl (2S)-2-carbamoylpyrrolidine-1-carboxylate
  • (S)-1-N-Cbz-prolinamide
  • (S)-benzyl 2-carbamoylpyrrolidine-1-carboxylate
  • 2-(aminocarbonyl)-1-Pyrrolidinecarboxylic acid phenylmethyl ester
  • Cbz-L-prolinamide
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