CAS 34080-08-5
:(20S)-Protopanaxatriol
Description:
(20S)-Protopanaxatriol is a triterpenoid saponin primarily derived from ginseng, particularly from the roots of Panax ginseng. It is characterized by its unique molecular structure, which includes a steroid-like framework with multiple hydroxyl groups, contributing to its bioactivity. This compound is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and immunomodulatory effects. (20S)-Protopanaxatriol has been studied for its role in enhancing cognitive function and its potential protective effects against various diseases, including cancer and cardiovascular conditions. Its solubility in organic solvents and limited solubility in water are notable physical properties, influencing its bioavailability and therapeutic applications. The compound's mechanism of action often involves modulation of signaling pathways and interaction with cellular receptors, making it a subject of interest in both traditional medicine and modern pharmacology. Overall, (20S)-Protopanaxatriol exemplifies the complex interplay between natural products and health, highlighting the importance of phytochemicals in therapeutic development.
Formula:C30H52O4
InChI:InChI=1S/C30H52O4/c1-18(2)10-9-13-30(8,34)19-11-15-28(6)24(19)20(31)16-22-27(5)14-12-23(33)26(3,4)25(27)21(32)17-29(22,28)7/h10,19-25,31-34H,9,11-17H2,1-8H3/t19-,20+,21-,22+,23-,24-,25-,27+,28+,29+,30-/m0/s1
InChI key:InChIKey=SHCBCKBYTHZQGZ-CJPZEJHVSA-N
SMILES:C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@]([C@@H](O)C2)(C(C)(C)[C@@H](O)CC4)[H])[H])[H]
Synonyms:- (20S)-Protopanaxatriol
- (3Beta,6Alpha,12Beta,14Beta)-Dammar-24-Ene-3,6,12,20-Tetrol
- (3b,6a,12b)-Dammar-24-ene-3,6,12,20-tetrol,(3beta,6alpha,12beta)-Protopanaxatriol
- (3Β,6Α,12Β)-Dammar-24-Ene-3,6,12,20-Tetrol
- 20(S)-Appt
- Dammar-24-ene-3,6,12,20-tetrol, (3β,6α,12β)-
- Dammar-24-ene-3β,6α,12β,20-tetrol, (20S)-
- Panaxoside A aglycone A<sub>φ</sub>
- Panaxoside A aglycone Aφ
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Found 8 products.
(20S)-Protopanaxatriol
CAS:(20S)-Protopanaxatriol analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Formula:C30H52O4Purity:(HPLC) ≥95%Color and Shape:PowderMolecular weight:476.74(20S)-Protopanaxatriol
CAS:<p>(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid</p>Formula:C30H52O4Purity:95% - 99%Color and Shape:SolidMolecular weight:476.73Protopanaxatriol
CAS:Cyclic alcoholFormula:C30H52O4Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:476.7420S-Protopanaxatriol
CAS:Controlled Product<p>20S-Protopanaxatriol is a drug that has been shown to have anticancer effects in human HL60 cells. It inhibits the expression of cytokines and inflammatory mediators, such as tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and IL-8. 20S-protopanaxatriol also has anti-inflammatory properties due to its ability to inhibit toll-like receptor 4 (TLR4) activity. The drug may also be used for the treatment of chronic inflammation, arthritis, and other diseases related to TLR4 activation. This compound is an active ingredient found in ginseng and ginsenosides. These natural compounds are thought to work by binding to a response element on DNA and regulating the transcription of genes involved in immune responses or cell growth.</p>Formula:C30H52O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:476.73 g/mol(20S)-Protopanaxatriol (~91% HPLC)
CAS:Controlled Product<p>Applications (20S)-Protopanaxatriol acts as an inhibitor in the production of corticosteroids in fasciculata cells. Used in the clinical treatment of heart diseases.<br>References Hasegawa, E. et al.: Life Sci., 92, 687 (2013); Wang, X. et al.: Pathobiol., 79, 285 (2012);<br></p>Formula:C30H52O4Color and Shape:NeatMolecular weight:476.732
