CAS 34097-16-0

Clocortolone pivalate

Description:

Clocortolone pivalate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is primarily used in dermatological formulations to treat various skin conditions, including eczema and dermatitis. The substance is characterized by its ability to reduce inflammation and alleviate symptoms such as redness, itching, and swelling. Clocortolone pivalate is typically formulated as a topical cream or ointment, allowing for localized treatment with minimal systemic absorption. Its mechanism of action involves the inhibition of inflammatory mediators and modulation of immune responses. The compound is known for its relatively low potency compared to other corticosteroids, making it suitable for sensitive skin areas. Additionally, it has a favorable safety profile, with a lower risk of side effects associated with long-term use. As with any corticosteroid, it is important to use clocortolone pivalate as directed to minimize potential adverse effects, such as skin thinning or systemic absorption. Overall, clocortolone pivalate serves as an effective option in the management of inflammatory skin disorders.

Formula:C₂₇H₃₆ClFO₅

InChI:InChI=1S/C27H36ClFO5/c1-14-9-16-17-11-19(29)18-10-15(30)7-8-26(18,6)27(17,28)21(32)12-25(16,5)22(14)20(31)13-34-23(33)24(2,3)4/h7-8,10,14,16-17,19,21-22,32H,9,11-13H2,1-6H3/t14-,16+,17+,19+,21+,22-,25+,26+,27+/m1/s1

InChI key:InChIKey=SXYZQZLHAIHKKY-GSTUPEFVSA-N

SMILES:Cl[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@@H](C(COC(C(C)(C)C)=O)=O)[C@H](C)C3)[H])(C[C@H](F)C=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

(6Alpha,11Beta,16Alpha)-9-Chloro-6-Fluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl 2,2-Dimethylpropanoate
(6Alpha,8Xi,10Xi,13Xi,14Xi,16Alpha,17Xi)-9-Chloro-6-Fluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl 2,2-Dimethylpropanoate
(6α,11β,16α)-9-Chloro-21-(2,2-dimethyl-1-oxopropoxy)-6-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione
21-Pivalate De 9-Chloro-6Α-Fluoro-11Β,21-Dihydroxy-16Α-Methylpregna-1,4-Diene-3,20-Dione
21-Pivalato De 9-Cloro-6Α-Fluoro-11Β,21-Dihidroxi-16Α-Metilpregna-1,4-Dieno-3,20-Diona
9-Chlor-6α-fluor-11β,21-dihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-pivalat
9-Chloro-6Α-Fluoro-11Β,21-Dihydroxy-16Α-Methylpregna-1,4-Diene-3,20-Dione 21-Pivalate
Cl 68
Clocortolone trimethylacetate
Cloderm
Pregna-1,4-diene-3,20-dione, 9-chloro-21-(2,2-dimethyl-1-oxopropoxy)-6-fluoro-11-hydroxy-16-methyl-, (6α,11β,16α)-
Pregna-1,4-diene-3,20-dione, 9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methyl-, 21-pivalate
Purantix
Sh 863
See more synonyms

Purity (%)

100

Found 7 products.

+ Info
Clocortolone Pivalate
CAS:
- 34097-16-0
Halogenated derivatives of adrenal cortical hormones
Formula:C₂₇H₃₆ClFO₅
Color and Shape:White Yellow Powder
Molecular weight:494.22353
Ref: 45-1138507
+ Info
CLOCORTOLONE PIVALATE (200 MG)
CAS:
- 34097-16-0
Formula:C₂₇H₃₆ClFO₅
Purity:98%
Color and Shape:Solid
Molecular weight:495.0231
Ref: IN-DA00C9ZT
5mg
114.00€
VAT not included
Add to cart
25mg
242.00€
VAT not included
Add to cart
100mg
To inquire
Add to cart
+ Info
Clocortolone Pivalate
CAS:
- 34097-16-0
Formula:C₂₇H₃₆ClFO₅
Color and Shape:Off-White Solid
Molecular weight:495.03
Ref: 4Z-F-071005
5mg
To inquire
Add to cart
10mg
444.00€
VAT not included
Add to cart
25mg
635.00€
VAT not included
Add to cart
50mg
825.00€
VAT not included
Add to cart
100mg
To inquire
Add to cart
+ Info
Clocortolone Pivalate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 34097-16-0
Formula:C₂₇H₃₆ClFO₅
Color and Shape:Neat
Molecular weight:495.02
Ref: 86-MM3743.00
250mg
To inquire
Add to cart
+ Info
Clocortolone Pivalate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 34097-16-0
<p>Applications Clocortolone Pivalate is a corticosteroid used in the treatment of atopic dermatitis.<br>References Torok, H.M. et al.: Cutis, 72, 161 (2003); Svensson, A. et al.: Curr. Med. Res. Opin., 27, 1395 (2011):<br></p>
Formula:C₂₇H₃₆ClFO₅
Color and Shape:Neat
Molecular weight:495.02
Ref: TR-C583810
5mg
793.00€
VAT not included
Add to cart
10mg
1,252.00€
VAT not included
Add to cart
500µg
147.00€
VAT not included
Add to cart
+ Info
Clocortolone pivalate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 34097-16-0
Clocortolone pivalate is a synthetic corticosteroid that has anti-inflammatory properties and is used to treat allergic reactions. Clocortolone pivalate is not active against bacterial infections. The drug has been shown to be effective for the treatment of inflammatory bowel disease in children and adults, but it does not appear to be as effective in the long-term as other treatments. This may be due to its inability to inhibit the production of pro-inflammatory cytokines such as TNF-α or IL-1β. Clocortolone pivalate also binds to the adenosine receptor, which may explain its clinical response.
Formula:C₂₇H₃₆ClFO₅
Purity:Min. 95%
Color and Shape:White Powder
Molecular weight:495.02 g/mol
Ref: 3D-FC20492
100mg
135.00€
VAT not included
Add to cart
+ Info
Clocortolone pivalate
CAS:
- 34097-16-0
Clocortolone pivalate, a synthetic steroid, treats dermatitis and psoriasis.
Formula:C₂₇H₃₆ClFO₅
Color and Shape:Solid
Molecular weight:495.02
Ref: TM-T72391