CAS 34118-92-8

Acecainide hydrochloride

Description:

Acecainide hydrochloride is a pharmaceutical compound primarily used as an antiarrhythmic agent, particularly in the treatment of certain types of cardiac arrhythmias. It is a member of the class of drugs known as sodium channel blockers, which work by inhibiting the influx of sodium ions during the cardiac action potential, thereby stabilizing the cardiac membrane and reducing excitability. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Its chemical structure includes a piperidine ring, contributing to its pharmacological properties. Acecainide hydrochloride is typically administered orally or intravenously, depending on the clinical scenario. As with many medications, it may have side effects, including potential impacts on cardiac function, necessitating careful monitoring of patients during treatment. Overall, acecainide hydrochloride plays a significant role in managing arrhythmias, contributing to improved cardiac health in affected individuals.

Formula: C₁₅H₂₃N₃O₂·ClH

InChI: InChI=1S/C15H23N3O2.ClH/c1-4-18(5-2)11-10-16-15(20)13-6-8-14(9-7-13)17-12(3)19;/h6-9H,4-5,10-11H2,1-3H3,(H,16,20)(H,17,19);1H

InChI key: InChIKey=IYEWBJUCJHKLHD-UHFFFAOYSA-N

SMILES: C(NCCN(CC)CC)(=O)C1=CC=C(NC(C)=O)C=C1.Cl

Synonyms:

• N-Acetylprocainamide hydrochloride
• Benzamide, 4-(acetylamino)-N-[2-(diethylamino)ethyl]-, monohydrochloride
• N-Acetylprocaine amide hydrochloride
• Acetanilide, 4′-[[2-(diethylamino)ethyl]carbamoyl]-, monohydrochloride
• Benzamide, 4-(acetylamino)-N-[2-(diethylamino)ethyl]-, hydrochloride (1:1)

N-Acetylprocainamide HCl

CAS: 34118-92-8

Formula: C₁₅H₂₄ClN₃O₂

Purity: %

Color and Shape: Solid

Molecular weight: 313.8230

Ref: IN-DA003SP6

Acecainide hydrochloride

CAS: 34118-92-8

Acecainide hydrochloride

Purity: ≥98%

Molecular weight: 313.83g/mol

Ref: 54-BUP10789

N-Acetylprocainamide hydrochloride

CAS: 34118-92-8

Formula: (CH₃CONH)C₆H₄CONHCH₂CH₂N(C₂H₅)₂·HCl

Molecular weight: 313.82

Ref: 7W-GL6345

Acecainide hydrochloride

CAS: 34118-92-8

Acecainide hydrochloride (NAPA) is the major hepatic metabolite of procainamide.Cost-effective and quality-assured.

Formula: C₁₅H₂₄ClN₃O₂

Purity: 98.023% - 99.81%

Color and Shape: Solid

Molecular weight: 313.83

Ref: TM-T3575

N-Acetylprocainamide Hydrochloride

Controlled Product

CAS: 34118-92-8

Stability Very Hygroscopic
Applications N-Acetylprocainamide Hydrochloride is an antiarrhythmic agent and a metabolite of Procainamide (P755130). Procainamide is a drug used for both supraventricular and ventricular arrhythmias. For example, it can be used to convert new-onset atrial fibrillation, though it is suboptimal for this purpose. It can also be used to treat Wolff-Parkinson-White syndrome by prolonging the refractory period of the accessory pathway.
References Fenster, P., et al.: Am. Heart J.. 106, 501(1983); Sellers Jr, T. et al.: Circulation 55, 15 (1983)

Formula: C₁₅H₂₄ClN₃O₂

Color and Shape: Neat

Molecular weight: 313.82

Ref: TR-A188150