CAS 3413-58-9

Cinchonan-9-ol, 6′-ethoxy-10,11-dihydro-, hydrochloride (1:1), (8α,9R)-

Description:

Cinchonan-9-ol, 6′-ethoxy-10,11-dihydro-, hydrochloride (1:1), (8α,9R)- is a chemical compound derived from the cinchona alkaloids, which are known for their medicinal properties, particularly in treating malaria. This compound features a complex bicyclic structure typical of cinchona derivatives, characterized by a quinoline framework. The presence of the ethoxy group at the 6′ position enhances its solubility and bioactivity. As a hydrochloride salt, it is typically more stable and soluble in aqueous solutions, making it suitable for pharmaceutical applications. The specific stereochemistry indicated by (8α,9R) suggests a particular three-dimensional arrangement of atoms, which can significantly influence the compound's biological activity and interaction with biological targets. Overall, this compound exemplifies the structural diversity and potential therapeutic applications of cinchona-derived alkaloids in medicinal chemistry.

Formula: C₂₁H₂₈N₂O₂·ClH

InChI: InChI=1S/C21H28N2O2.ClH/c1-3-14-13-23-10-8-15(14)11-20(23)21(24)17-7-9-22-19-6-5-16(25-4-2)12-18(17)19;/h5-7,9,12,14-15,20-21,24H,3-4,8,10-11,13H2,1-2H3;1H/t14-,15-,20-,21+;/m0./s1

InChI key: InChIKey=QNRATNLHPGXHMA-XZHTYLCXSA-N

SMILES: [C@@H](O)(C=1C2=C(C=CC(OCC)=C2)N=CC1)[C@]3([N@@]4C[C@H](CC)[C@](C3)(CC4)[H])[H].Cl

Synonyms:

• (3alpha,9R)-6'-ethoxy-10,11-dihydrocinchonan-1-ium-9-ol
• (9R)-6'-ethoxy-10,11-dihydrocinchonan-1-ium-9-ol
• 6'-Ethoxy-10,11-Dihydrocinchonan-9-Ol
• Cinchonan-9-ol, 6'-ethoxy-10,11-dihydro-, monohydrochloride, (8alpha,9R)- (9CI)
• Cinchonan-9-ol, 6′-ethoxy-10,11-dihydro-, hydrochloride (1:1), (8α,9R)-
• Cinchonan-9-ol, 6′-ethoxy-10,11-dihydro-, monohydrochloride, (8α,9R)-
• Ethylhydrocupreine HCl
• Hydrocupreine, O-6'-ethyl-, monohydrochloride (VAN)
• Hydrocupreine, O-ethyl-, hydrochloride
• Hydrocupreine, O^6′-ethyl-, monohydrochloride
• Hydrocupreine, ethyl ester, hydrochloride
• Neumolisina
• Nsc 5361
• Numoquin hydrochloride
• O-Ethylhydrocupreine hydrochloride
• Optochin hydrochloride
• Optoquin hydrochloride
• Optoquinhydrochloride
• Rhombic

Ethylhydrocupreine hydrochloride, 97%

CAS: 3413-58-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₃H₃₃ClN₂O₂

Purity: 97%

Color and Shape: White to cream, Crystals or powder or crystalline powder

Molecular weight: 404.98

Ref: 02-B21627

Ethylhydrocupreine (hydrochloride)

CAS: 3413-58-9

Formula: C₂₁H₂₉ClN₂O₂

Purity: 98%

Molecular weight: 376.9202

Ref: IN-DA003QJD

Ethylhydrocupreine hydrochloride

CAS: 3413-58-9

Ethylhydrocupreine hydrochloride

Purity: ≥98%

Molecular weight: 376.92g/mol

Ref: 54-BUP11789

Ethylhydrocupreine hydrochloride

CAS: 3413-58-9

Formula: C₂₁H₂₆N₂O₂HCl

Molecular weight: 374.91

Ref: 7W-GP2956

Ethylhydrocupreine hydrochloride

CAS: 3413-58-9

Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a derivative of quinine with antimicrobial activity against Streptococcus pneumoniae.

Formula: C₂₁H₂₉ClN₂O₂

Purity: 99.73% - 99.86%

Color and Shape: Solid

Molecular weight: 376.92

Ref: TM-T40417

Ethylhydrocupreine HCl

CAS: 3413-58-9

Ethylhydrocupreine HCl is a cavity treatment that is used to treat cancer. It is a laboratory diagnosis, which means it can be used to diagnose and monitor the progression of cancer. Ethylhydrocupreine HCI has been shown to have hemolytic activity against erythrocytes and has been shown in laboratory experiments to inhibit the growth of pneumococcus and other bacteria by interfering with DNA synthesis. Ethylhydrocupreine HCI is being studied as an anticancer agent that may prevent the spread of cancer cells. The drug binds to dsDNA, inhibiting replication and transcription, leading to cell death. Ethylhydrocupreine HCI also inhibits protein synthesis by binding to RNA polymerase and preventing elongation of RNA chains.

Formula: C₂₁H₂₈N₂O₂·HCl

Purity: Min. 95%

Color and Shape: White Yellow Powder

Molecular weight: 376.92 g/mol

Ref: 3D-FE30579