CAS 3416-18-0

5-Hydroxyoxindole

Description:

5-Hydroxyoxindole is an organic compound characterized by its oxindole structure, which features a fused benzene and pyrrole ring system. It is a derivative of oxindole, with a hydroxyl group (-OH) positioned at the 5th carbon of the indole ring. This compound is typically a white to off-white solid and is soluble in polar solvents such as water and alcohols, owing to the presence of the hydroxyl group. 5-Hydroxyoxindole is of interest in various fields, including medicinal chemistry and biochemistry, due to its potential biological activities, including roles in neurotransmitter metabolism and as a precursor in the synthesis of other biologically active compounds. Its CAS number, 3416-18-0, is used for identification in chemical databases and regulatory contexts. As with many organic compounds, its reactivity can be influenced by the functional groups present, making it a subject of study for its potential applications in pharmaceuticals and research.

Formula: C₈H₇NO₂

InChI: InChI=1/C8H7NO2/c10-6-1-2-7-5(3-6)4-8(11)9-7/h1-3,10H,4H2,(H,9,11)

InChI key: InChIKey=ZGTUSQAQXWSMDW-UHFFFAOYSA-N

SMILES: O=C1NC=2C(C1)=CC(O)=CC2

Synonyms:

• 1,3-Dihydro-5-hydroxy-2H-indol-2-one
• 2-Indolinone, 5-hydroxy-
• 2H-Indol-2-one, 1,3-dihydro-5-hydroxy-
• 5-Hydroxyindolin-2-One
• 5-Hydroxyoxindole
• 5-hydroxy-1,3-dihydro-2H-indol-2-one
• Oxindole, 5-hydroxy-
• 2,3-Dihydro-5-hydroxyindol-2-one
• 5-HYDROXY-2-INDOLINONE
• 5-Hydroxyindoline-2-one
• 5-HYDROXY-1,3-DIHYDRO-INDOL-2-ONE
• 5-Hydroxy-1H-indole-2(3H)-one
• 5-Hydroxy-2-oxyindole
• 5-Hydroxy-2-oxindole
• 5-Hydroxy-2,3-dihydro-1H-indole-2-one

5-Hydroxyindolin-2-one

CAS: 3416-18-0

Formula: C₈H₇NO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 149.1467

Ref: IN-DA0037NH

5-Hydroxyoxindole

CAS: 3416-18-0

5-Hydroxyoxindole

Purity: 95%

Molecular weight: 149.15g/mol

Ref: 54-OR910617

5-Hydroxyoxindole

CAS: 3416-18-0

5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1].

Formula: C₈H₇NO₂

Color and Shape: Solid

Molecular weight: 149.15

Ref: TM-T37710

5-Hydroxyoxindole

CAS: 3416-18-0

5-Hydroxyoxindole (5HO) is a naturally occurring molecule that is found in oxindole and other indoles. It has been shown to have regulatory effects on inflammatory diseases, notably in the treatment of colitis. 5HO possesses significant cytotoxicity against carcinoma cells and also has radical scavenging activity. This compound can be synthesized using a solid-phase synthesis method. The presence of 5HO in skin cells has been correlated with the production of skin pigment called melanin. In addition, this molecule has been shown to bind to picolinic acid, which may contribute to its anti-inflammatory properties. 5HO is also present in neurologic disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.

Formula: C₈H₇NO₂

Purity: Min. 95%

Color and Shape: Beige Powder

Molecular weight: 149.15 g/mol

Ref: 3D-FH52473

5-Hydroxyindolin-2-one

CAS: 3416-18-0

Formula: C₈H₇NO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 149.149

Ref: 10-F209035