CAS 34183-22-7

Propafenone hydrochloride

Description:

Propafenone hydrochloride is a pharmaceutical compound primarily used as an antiarrhythmic agent for the treatment of certain types of irregular heartbeats, specifically atrial fibrillation and ventricular tachycardia. It is classified as a Class IC antiarrhythmic drug, which means it works by blocking sodium channels in cardiac cells, thereby stabilizing the cardiac membrane and reducing excitability. The substance appears as a white to off-white crystalline powder and is soluble in water and alcohol, which facilitates its formulation in various dosage forms, such as tablets and oral solutions. Propafenone hydrochloride is known for its ability to prolong the refractory period in cardiac tissues, thus helping to restore normal heart rhythm. It may also exhibit beta-blocking properties, contributing to its therapeutic effects. Common side effects can include dizziness, fatigue, and gastrointestinal disturbances. Due to its pharmacological profile, careful monitoring is required during treatment, especially in patients with pre-existing heart conditions or those taking other medications that may interact with its metabolism.

Formula: C₂₁H₂₇NO₃·ClH

InChI: InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H

InChI key: InChIKey=XWIHRGFIPXWGEF-UHFFFAOYSA-N

SMILES: O(CC(CNCCC)O)C1=C(C(CCC2=CC=CC=C2)=O)C=CC=C1.Cl

Synonyms:

• 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one hydrochloride
• 1-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-, hydrochloride
• 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride (1:1)
• 1-{2-[2-Hydroxy-3-(Propylamino)Propoxy]Phenyl}-3-Phenylpropan-1-One Hydrochloride (1:1)
• 2'-(2-Hydroxy-3-(propylamino)propoxy)-3-phenylpropiophenone hydrochloride
• Arythmol
• Baxarytmon
• Fenoprain
• Pronon
• Propafenon hydrochlorid
• Propafenon hydrochlorid [German]
• Propafenone hydrochloride
• Propafenone hydrochloride [USAN:JAN]
• Propiophenone, 2'-(2-hydroxy-3-(propylamino)propoxy)-3-phenyl-, hydrochloride
• Rhythmonorm
• Rythmol
• Rythmol SR
• Rytmonorm
• Sa 79
• Unii-33Xch0Hocd
• Wz 884
• 2’-(2-hydroxy-3-(propylamino)propoxy)-3-phenyl-propiophenonhydrochloride
• 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride (9CI)
• Rytmonor
• 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanonhydroc
• 1-[2-(2-HYDROXY-3-[PROPYLAMINO]-PROPOXY)PHENYL]-3-PHENYL-1-PROPANONE HYDROCHLORIDE
• 2’-(2-hydroxy-3-(propylamino)propoxy)-3-phenylpropiophenonehydrochloride
• PROPAFENONE HCL
• sa79
• Propiophenone, 2'-[2-hydroxy-3-(propylamino)propoxy]-3-phenyl-, hydrochloride (8CI)
• wz884

Propafenone Hydrochloride

CAS: 34183-22-7, 54063-53-5

Formula: C₂₁H₂₇NO₃·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 377.91

Ref: 3B-P2301

Propafenone Hydrochloride

CAS: 34183-22-7

Color and Shape: Neat

Ref: 61-FOR0405.00

PROPAFENONE HYDROCHLORIDE CRS

CAS: 34183-22-7

PROPAFENONE HYDROCHLORIDE CRS

Formula: C₂₁H₂₈ClNO₃

Color and Shape: White. Colourless Crystals. Powder.

Molecular weight: 377.9049

Ref: 41-Y0000455

Propafenone Hydrochloride

CAS: 34183-22-7

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₂₁H₂₇NO₃·ClH

Color and Shape: Colorless White Powder

Molecular weight: 377.17577

Ref: 45-1570304

1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride

CAS: 34183-22-7

Formula: C₂₁H₂₈ClNO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 377.9049

Ref: IN-DA00391F

Propafenone HCl

CAS: 34183-22-7

Formula: C₂₁H₂₇NO₃·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 341.45 36.46

Ref: 4Z-P-1512

Propafenone hydrochloride

CAS: 34183-22-7

Propafenone hydrochloride

Purity: ≥98%

Molecular weight: 377.9g/mol

Ref: 54-BUP17652

1-[2-[2-Hydroxy-3-(Propylamino)Propoxy]Phenyl]-3-Phenylpropan-1-One Hydrochloride

CAS: 34183-22-7

1-[2-[2-Hydroxy-3-(Propylamino)Propoxy]Phenyl]-3-Phenylpropan-1-One Hydrochloride

Purity: 98%

Molecular weight: 377.9g/mol

Ref: 54-OR1030254

Propafenone hydrochloride, 10mM (in DMSO)

CAS: 34183-22-7

Propafenone hydrochloride, 10mM (in DMSO)

Purity: ≥98%

Molecular weight: 377.9g/mol

Ref: 54-BUP20003

Propafenone hydrochloride

CAS: 34183-22-7

Formula: C₂₁H₂₇NO₃·HCl

Purity: 98.0 - 102.0 % (C21H27NO3 · HCl, dried basis)

Color and Shape: Colourless crystals or white crystalline powder

Molecular weight: 377.90

Ref: 7W-GP3270

Propafenone Hydrochloride

CAS: 34183-22-7

Formula: C₂₁H₂₇NO₃·ClH

Color and Shape: White To Off-White

Molecular weight: 377.90

Ref: 86-MM0405.00

Propafenone hydrochloride

CAS: 34183-22-7

Formula: C₂₁H₂₇NO₃·ClH

Color and Shape: Neat

Molecular weight: 377.90

Ref: 04-C16385000

Propafenone hydrochloride

CAS: 34183-22-7

Propafenone hydrochloride (Arythmol8) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial.

Formula: C₂₁H₂₇NO₃·HCl

Purity: 99.67%

Color and Shape: White Solid

Molecular weight: 377.9

Ref: TM-T6955

Propafenone Hydrochloride

Controlled Product

CAS: 34183-22-7

Applications Sodium channel blocker. Antiarrhythmic (class IC).
References Hollmann, M., et al.: Arzneim.-Forsch., 33, 763 (1983), Bryson, H. M., et al.:Drugs, 45, 85 (1993), Rae, A. P., et al.: Am. J. Cardiol., 82, 59N (1998),

Formula: C₂₁H₂₇NO₃·ClH

Color and Shape: White To Off-White

Molecular weight: 377.90

Ref: TR-P757500

Propafenone HCl - Bio-X ™

CAS: 34183-22-7

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₂₁H₂₈ClNO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 377.9 g/mol

Ref: 3D-BP300114

1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride

CAS: 34183-22-7

Formula: C₂₁H₂₈ClNO₃

Purity: 95%+

Molecular weight: 377.91

Ref: 10-F358367

Propafenone HCl

CAS: 34183-22-7

Propafenone HCl is a class Ia antiarrhythmic drug that is used to treat atrial fibrillation and other cardiac arrhythmias. It has a high solubility in water, which makes it suitable for intravenous administration. The binding constants of propafenone to the cardiac muscle and myocardial cells are relatively high. This drug has also been shown to be safe in pediatric patients with congestive heart failure. Propafenone HCl has been shown to have an adverse effect on some people, causing serious side effects such as congestive heart failure or hypersensitivity reactions.

Formula: C₂₁H₂₈ClNO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 377.9 g/mol

Ref: 3D-FP27186