CAS 342-10-9

Kallidin

Description:

Kallidin, also known as Lysyl-bradykinin, is a peptide that plays a significant role in the regulation of blood pressure and inflammatory responses. It is a member of the kinin family, which are biologically active peptides derived from kininogen through the action of specific enzymes. Kallidin is characterized by its ability to induce vasodilation, increase vascular permeability, and stimulate pain receptors, contributing to its role in inflammatory processes. The peptide consists of a sequence of amino acids, with lysine being a key component that distinguishes it from other kinins like bradykinin. Kallidin is produced in the body in response to tissue injury or stress, and its effects are mediated through specific receptors known as bradykinin receptors. Due to its physiological functions, kallidin is of interest in various fields, including pharmacology and cardiovascular research. Its CAS number, 342-10-9, is used for identification in chemical databases and regulatory contexts.

Formula: C₅₆H₈₅N₁₇O₁₂

InChI: InChI=1/C56H85N17O12/c57-24-8-7-18-36(58)46(76)67-37(19-9-25-63-55(59)60)51(81)73-29-13-23-44(73)53(83)72-28-11-21-42(72)49(79)65-32-45(75)66-39(30-34-14-3-1-4-15-34)47(77)70-41(33-74)52(82)71-27-12-22-43(71)50(80)69-40(31-35-16-5-2-6-17-35)48(78)68-38(54(84)85)20-10-26-64-56(61)62/h1-6,14-17,36-44,74H,7-13,18-33,57-58H2,(H,65,79)(H,66,75)(H,67,76)(H,68,78)(H,69,80)(H,70,77)(H,84,85)(H4,59,60,63)(H4,61,62,64)

SMILES: c1ccc(cc1)CC(C(=NC(CO)C(=O)N1CCCC1C(=NC(Cc1ccccc1)C(=NC(CCCNC(=N)N)C(=O)O)O)O)O)N=C(CN=C(C1CCCN1C(=O)C1CCCN1C(=O)C(CCCNC(=N)N)N=C(C(CCCCN)N)O)O)O

Synonyms:

• Bradykinin, N2-L-lysyl-
• lysyl-N~5~-(diaminomethylidene)ornithylprolylprolylglycylphenylalanylserylprolylphenylalanyl-N~5~-(diaminomethylidene)ornithine

Lys-Bradykinin

CAS: 342-10-9

Endogenous bradykinin receptor agonist

Formula: C₅₆H₈₅N₁₇O₁₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1188.38

Ref: TM-TP2268

2-[[2-[[1-[2-[[2-[[2-[[1-[1-[2-(2,6-Diaminohexanoylamino)-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2- carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]a

CAS: 342-10-9

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₅₆H₈₅N₁₇O₁₂

Molecular weight: 1,188.38 g/mol

Ref: 3D-PP50785

Lysyl-Bradykinin (Kallidin) (Human, Bovine)

Controlled Product

CAS: 342-10-9

Lysyl-bradykinin (kallidin) is a peptide that is a potent activator of non-selective cation channels. It has been shown to activate potassium channels and calcium channels, but not sodium channels. The activation by lysyl-bradykinin leads to an increase in the permeability of the membrane, which can lead to release of neurotransmitters from nerve endings. Lysyl-bradykinin also has been shown to be an inhibitor of protein interactions with the receptor in certain cell lines. The antibody used to measure this inhibition is L1420.

Formula: C₅₆H₈₅N₁₇O₁₂

Purity: Min. 95%

Molecular weight: 1,188.40 g/mol

Ref: 3D-PBK-4008-V

Lys-Bradykinin acetate salt

CAS: 342-10-9

Lys-Bradykinin is a peptide that is a member of the group of kinins. It has been shown to be effective at inhibiting the activity of kallikrein, which is an enzyme that converts kininogen to bradykinin. This inhibition lowers the levels of bradykinin in the blood and may be used as a diagnostic tool for identifying diseases such as congestive heart failure, pulmonary edema, and acute renal failure. Lys-Bradykinin can also be used as a model system for studying kinins and their biological effects on various systems. For example, it has been shown to have natriuretic properties in humans by increasing levels of erythropoietin and ANP.

Formula: C₅₆H₈₅N₁₇O₁₂

Purity: Min. 95%

Molecular weight: 1,188.38 g/mol

Ref: 3D-FL108620

Lys-Bradykinin

CAS: 342-10-9

Kallidin is the precursor of the vasodilator bradykinin.

Formula: C₅₆H₈₅N₁₇O₁₂

Purity: 96.38%

Color and Shape: White Lyophilisate

Molecular weight: 1188.4

Ref: 01-4003280