CAS 3420-72-2

2′-Hydroxy-4,4′,6′-trimethoxychalcone

Description:

2′-Hydroxy-4,4′,6′-trimethoxychalcone, with the CAS number 3420-72-2, is a synthetic organic compound belonging to the chalcone class, characterized by its distinctive structure that includes a chalcone backbone with three methoxy groups and a hydroxyl group. This compound typically exhibits a yellow to orange color, which is common among chalcones due to their conjugated double bond systems. It is known for its potential biological activities, including antioxidant, anti-inflammatory, and anticancer properties, making it of interest in pharmaceutical research. The presence of multiple methoxy groups enhances its solubility in organic solvents and may influence its reactivity and interaction with biological targets. Additionally, the hydroxyl group can participate in hydrogen bonding, potentially affecting its pharmacokinetic properties. Overall, 2′-Hydroxy-4,4′,6′-trimethoxychalcone represents a valuable compound for further exploration in medicinal chemistry and natural product synthesis.

Formula: C₁₈H₁₈O₅

InChI: InChI=1S/C18H18O5/c1-21-13-7-4-12(5-8-13)6-9-15(19)18-16(20)10-14(22-2)11-17(18)23-3/h4-11,20H,1-3H3

InChI key: InChIKey=CGIBCVBDFUTMPT-UHFFFAOYSA-N

SMILES: O(C)C1=C(C(C=CC2=CC=C(OC)C=C2)=O)C(O)=CC(OC)=C1

Synonyms:

• (2E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one
• 1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one
• 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-
• 2′-Hydroxy-4,4′,6′-trimethoxychalcone
• 4-Methoxybenzylidene(4,6-dimethoxy-2-hydroxyacetophenone)
• Chalcone, 2′-hydroxy-4,4′,6′-trimethoxy-
• NSC 37445

Flavokawain A

CAS: 3420-72-2, 37951-13-6

Formula: C₁₈H₁₈O₅

Purity: >98.0%(GC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 314.34

Ref: 3B-H1571

Flavokawain A

CAS: 3420-72-2

Flavokawain A analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₈H₁₈O₅

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 314.34

Ref: 11-1043

1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one

CAS: 3420-72-2

Formula: C₁₈H₁₈O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 314.3325

Ref: IN-DA003GA3

Flavokawain A

CAS: 3420-72-2

Flavokawain A

Purity: 98%

Molecular weight: 314.33g/mol

Ref: 54-OR1029232

Flavokawain A

CAS: 3420-72-2

Flavokawain A

Purity: ≥95%

Molecular weight: 314.33g/mol

Ref: 54-BUP14698

(Iso)-Flavokawain A

CAS: 3420-72-2

NSC-37445 shows anti-tumor properties; Flavokawain A may reduce inflammation by hindering specific signaling in macrophages.

Formula: C₁₈H₁₈O₅

Purity: 97.1% - 99.72%

Color and Shape: Solid

Molecular weight: 314.332

Ref: TM-T3S0737

2'-Hydroxy-4,4',6'-trimethoxychalcone

Controlled Product

CAS: 3420-72-2

Formula: C₁₈H₁₈O₅

Color and Shape: Neat

Molecular weight: 314.33

Ref: TR-H214235

2'-Hydroxy-4,4',6'-trimethoxychalcone

CAS: 3420-72-2

2'-Hydroxy-4,4',6'-trimethoxychalcone is a chalcone derivative, which is a type of flavonoid compound often found in plants. This compound is commonly sourced from various kinds of plant species, particularly those belonging to the families Asteraceae and Fabaceae. It exhibits its activity primarily through the modulation of cellular oxidative stress pathways and inflammatory processes. Chalcones, including 2'-Hydroxy-4,4',6'-trimethoxychalcone, often act by inhibiting key enzymes involved in inflammation and neutralizing free radicals.

Formula: C₁₈H₁₈O₅

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 314.33 g/mol

Ref: 3D-FH67763