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CAS 342026-92-0

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Sipoglitazar

Description:
Sipoglitazar is a synthetic compound classified as a thiazolidinedione, primarily developed for the treatment of type 2 diabetes. It functions as a dual agonist of peroxisome proliferator-activated receptors (PPARs), specifically PPAR-α and PPAR-γ, which play crucial roles in glucose and lipid metabolism. This dual action helps improve insulin sensitivity and regulate lipid profiles, making it beneficial for managing blood sugar levels and reducing cardiovascular risks associated with diabetes. Sipoglitazar has been noted for its potential to lower triglyceride levels and improve overall metabolic health. The compound is characterized by its unique chemical structure, which includes a thiazolidine ring, contributing to its biological activity. As with many pharmaceutical agents, its efficacy and safety profile are evaluated through clinical trials, and it may exhibit side effects typical of PPAR agonists, such as weight gain or fluid retention. Ongoing research continues to explore its full therapeutic potential and mechanisms of action in metabolic disorders.
Formula:C25H25N3O4S
Synonyms:
  • TAK 654
  • TAK-654
  • CS-1568
  • TAK654
  • 3-Ethoxy-1-[[4-[(2-phenyl-4-thiazolyl)Methoxy]phenyl]Methyl]-1H-pyrazole-4-propanoic Acid
  • Sipoglitazar
  • 3-[3-Ethoxy-1-[4-[(2-phenyl-1,3-thiazol-4-yl)Methoxy]benzyl]-1H-pyrazol-4-yl]propionic Acid
  • 1H-Pyrazole-4-propanoic acid, 3-ethoxy-1-[[4-[(2-phenyl-4-thiazolyl)methoxy]phenyl]methyl]-
  • 3-[3-Ethoxy-1-[4-(2-phenyl-4-thiazolylMethoxy)benzyl]-1H-pyrazol-4-yl]propionic Acid
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Found 2 products.
  • Sipoglitazar
    TRC
    + Info

    Sipoglitazar

    Controlled Product
    CAS:
    <p>Applications Sipoglitazar is a novel antidiabetic agent. Sipoglitazar displays triple agonistic activities on the human peroxisome proliferator-activated receptors, hPPAR-γ, -α, and -δ.<br>References Nishihara, M. et al.: Drug Metab. Dispos., 40, 249 (2012);<br></p>
    Formula:C25H25N3O4S
    Color and Shape:White To Off-White
    Molecular weight:463.55

    Ref: TR-S487800

    5mg
    1,849.00€
    500µg
    281.00€
  • Sipoglitazar
    Targetmol
    + Info

    Sipoglitazar

    CAS:
    <p>Sipoglitazar, a PPARγ agonist, is used potentially for the treatment of diabetes.</p>
    Formula:C25H25N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:463.55

    Ref: TM-T28783