CAS 34207-46-0

3,5-Diamino-4-chlorobenzonitrile

Description:

3,5-Diamino-4-chlorobenzonitrile, with the CAS number 34207-46-0, is an organic compound characterized by its aromatic structure, which includes a benzene ring substituted with two amino groups and a chloronitrile group. The presence of the amino groups (-NH2) indicates that it is a diamine, which can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. The chloronitrile group (-C≡N) contributes to its reactivity and potential applications in organic synthesis. This compound is typically a solid at room temperature and may exhibit moderate solubility in polar solvents due to the presence of the amino groups. It is often used in the synthesis of dyes, pharmaceuticals, and agrochemicals, owing to its functional groups that allow for further chemical modifications. Safety data should be consulted, as compounds with amino and halogen substituents can pose health risks, and appropriate handling procedures should be followed in laboratory settings.

Formula: C₇H₆ClN₃

InChI: InChI=1S/C7H6ClN3/c8-7-5(10)1-4(3-9)2-6(7)11/h1-2H,10-11H2

InChI key: InChIKey=AJYCIEHSLYUBEI-UHFFFAOYSA-N

SMILES: C(#N)C1=CC(N)=C(Cl)C(N)=C1

Synonyms:

• TC 566
• 4-Chloro-3,5-diaminobenzonitrile
• 2-Chloro-5-cyano-m-phenylenediamine
• 3,5-Diamino-4-chlorobenzonitrile
• Benzonitrile, 3,5-diamino-4-chloro-

Lodoxamide Impurity 6

CAS: 34207-46-0

Formula: C₇H₆ClN₃

Molecular weight: 167.60

Ref: 4Z-L-119014

3,5-Diamino-4-chlorobenzonitrile-15N2

Controlled Product

CAS: 34207-46-0

Applications 3,5-Diamino-4-chlorobenzonitrile-15N2 is an intermediate in synthesizing Lodoxamide-15N2,d2 (L469367), a labelled form of Lodoxamide. It is an antiallergic drug that acts as a mast cell stabilizer. It is effective in the treatment of allergic conjunctivitis and in decreasing vascular permeability.
References Ciprandi, G., et al.: Allergy, 51(12), 946-951 (1996); Bayer, Atilla., et al.: Ophthalmologica, 217(2), 119-123 (2003)

Formula: C₇H₄Cl₁₅N₂NO₂

Color and Shape: Neat

Molecular weight: 199.565

Ref: TR-A630582

3,5-Diamino-4-chlorobenzonitrile

Controlled Product

CAS: 34207-46-0

Applications 3,5-Diamino-4-chlorobenzonitrile is used in the preparation of glycolic amide derivatives as allergy inhibitors and antiinflammatory agents
References Ban, M., et al.: Bioorg. Med. Chem., 6, 1069 (1998); Takasugi, H. et al.: J. Antibio., 36, 846 (1983); Ban, M. et al.: Bioorg. Med. Chem., 6, 1069 (1998);

Formula: C₇H₆ClN₃

Color and Shape: Neat

Molecular weight: 167.6

Ref: TR-D416205