CAS 3423-30-1

8-Ethyl-8-azabicyclo[3.2.1]octan-3-one

Description:

8-Ethyl-8-azabicyclo[3.2.1]octan-3-one, with the CAS number 3423-30-1, is a bicyclic compound characterized by its unique structural framework, which includes a nitrogen atom incorporated into a bicyclic system. This compound features an ethyl group at the 8-position and a ketone functional group at the 3-position, contributing to its chemical reactivity and potential applications. The bicyclic structure imparts rigidity, influencing its conformational properties and interactions with biological systems. Typically, such compounds may exhibit interesting pharmacological activities, making them of interest in medicinal chemistry. The presence of the azabicyclic framework suggests potential for interactions with neurotransmitter systems, which could be explored for therapeutic purposes. Additionally, the compound's solubility, stability, and reactivity can vary based on environmental conditions and the presence of other functional groups. Overall, 8-Ethyl-8-azabicyclo[3.2.1]octan-3-one represents a class of compounds that may have significant implications in drug design and development.

Formula: C₉H₁₅NO

InChI: InChI=1S/C9H15NO/c1-2-10-7-3-4-8(10)6-9(11)5-7/h7-8H,2-6H2,1H3

InChI key: InChIKey=NIEPDSXRYYXOIA-UHFFFAOYSA-N

SMILES: C(C)N1C2CC(=O)CC1CC2

Synonyms:

• 8-Ethylnortropinone
• 3-Nortropanone, 8-ethyl-
• 8-Ethyl-8-azabicyclo[3.2.1]octan-3-one
• N-Ethylnortropinone
• 8-Azabicyclo[3.2.1]octan-3-one, 8-ethyl-

8-Ethyl-8-azabicyclo[3.2.1]octan-3-one

CAS: 3423-30-1

8-Ethyl-8-azabicyclo[3.2.1]octan-3-one is a synthetic compound that is structurally similar to nicotine, which is found in the leaves of tobacco plants. It has been shown to have pharmacological activity as a nicotinic receptor agonist. 8-Ethyl-8-azabicyclo[3.2.1]octan-3-one has been used in the treatment of various types of cancer, including Hodgkin's disease and breast cancer, as well as for Parkinson's disease and Alzheimer's disease. 8EBAO also has antiemetic properties and can be used to treat motion sickness or postoperative nausea and vomiting. The drug is metabolized by CYP450 enzymes into tigloyloximes, which are then converted into pseudotropine or piperideine through the action of rhizogenes from Pseudomonas sp., Streptomyces sp.,

Formula: C₉H₁₅NO

Purity: Min. 95%

Molecular weight: 153.22 g/mol

Ref: 3D-DAA42330