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CAS 34235-82-0

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Tos-Lys(Z)-OH

Description:
Tos-Lys(Z)-OH, also known as Tosyl-Lysine(Z)-OH, is a protected form of the amino acid lysine, which is commonly used in peptide synthesis and biochemistry. The "Tos" prefix indicates the presence of a tosyl group, which serves as a protective group for the amino group of lysine, enhancing its stability and reactivity during chemical reactions. The "Z" denotes the benzyloxycarbonyl (Z) protecting group on the lysine side chain, which protects the amino group from unwanted reactions while allowing for selective deprotection later in the synthesis process. This compound is typically a white to off-white solid and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol. Its structure allows for the introduction of lysine into peptides while maintaining the integrity of the amino acid's functional groups. Tos-Lys(Z)-OH is widely utilized in the synthesis of peptides and proteins, particularly in the development of pharmaceuticals and bioconjugates, due to its ability to facilitate the formation of peptide bonds while providing stability during synthesis.
Formula:C21H26N2O6S
InChI:InChI=1/C21H26N2O6S/c1-16-10-12-18(13-11-16)30(27,28)23-19(20(24)25)9-5-6-14-22-21(26)29-15-17-7-3-2-4-8-17/h2-4,7-8,10-13,19,23H,5-6,9,14-15H2,1H3,(H,22,26)(H,24,25)/t19-/m0/s1
SMILES:Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCCN=C(O)OCc1ccccc1)C(=O)O
Synonyms:
  • Carbobenzoxytosyllysine
  • N^(epsilum)-Carbobenzoxy-N^(alpha)-tosyl-L-lysine
  • -Carbobenzoxy-
  • TOS-LYS(Z)-OH
  • Nepsilon-carbobenzoxy-N-α-Tosyl-L-Lysine
  • Nα-Tosyl-Nε-(benzyloxycarbonyl)-L-lysine
  • Nepsilon-Benzyloxycarbonyl-Nalpha-tosyl-L-lysine
  • Nε-Cbz-Nα-Tosyl-L-lysine
  • (S)-6-(((Benzyloxy)carbonyl)amino)-2-(4-methylphenylsulfonamido)hexanoic acid
  • TOSYL-N-EPSILON-Z-L-LYSINE
  • See more synonyms
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