CAS 3424-98-4

2'-Deoxy-L-thymidine

Description:

2'-Deoxy-L-thymidine, also known as L-thymidine, is a nucleoside that plays a crucial role in the structure of DNA. It consists of a thymine base attached to a deoxyribose sugar, specifically in the L-configuration. This compound is characterized by its ability to participate in the formation of DNA strands, where it pairs with adenine during DNA replication. The presence of the deoxyribose sugar distinguishes it from ribonucleosides, as it lacks a hydroxyl group at the 2' position. 2'-Deoxy-L-thymidine is soluble in water and exhibits a relatively stable structure under physiological conditions. Its CAS number, 3424-98-4, is used for identification in chemical databases. This compound is of interest in biochemical research and therapeutic applications, particularly in the study of nucleic acid metabolism and as a potential antiviral agent. Overall, 2'-Deoxy-L-thymidine is significant in molecular biology and genetics, contributing to our understanding of DNA synthesis and repair mechanisms.

Formula: C₁₀H₁₄N₂O₅

InChI: InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1

InChI key: InChIKey=IQFYYKKMVGJFEH-CSMHCCOUSA-N

SMILES: O=C1N([C@H]2O[C@@H](CO)[C@H](O)C2)C=C(C)C(=O)N1

Synonyms:

• 1-(2-Deoxy--L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
• 1-(2-Deoxy-β-<span class="text-smallcaps">L</span>-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
• 1-(2-deoxy--L-erythro-pentofuranosyl)thymine
• 1-(2-deoxy-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• 1-[(2S,4R,5S)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">L</span>-erythro-pentofuranosyl)-5-methyl-
• 2′-Deoxy-<span class="text-smallcaps">L</span>-thymidine
• <span class="text-smallcaps">L</span>-Deoxythymidine
• <span class="text-smallcaps">L</span>-Thymidine
• Beta-L-Thymidine
• Epavudine
• L-Thymidine
• Nv 02B
• Sebivo
• Telbivudine
• Telbivudine & its intermediates
• Telbivudine intermediates
• Thymine, 1-(2-deoxy-β-<span class="text-smallcaps">L</span>-erythro-pentofuranosyl)-
• Tyzeka
• β-<span class="text-smallcaps">L</span>-Thymidine
• 2′-Deoxy-L-thymidine
• 1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-methyl-

Telbivudine

CAS: 3424-98-4

Telbivudine (NV 02B) is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor.

Formula: C₁₀H₁₄N₂O₅

Purity: 99.39% - 99.81%

Color and Shape: White E Crystal Powder

Molecular weight: 242.23

Ref: TM-T1513

1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

CAS: 3424-98-4

Formula: C₁₀H₁₄N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 242.2286

Ref: IN-DA00I6RH

Telbivudine

CAS: 3424-98-4

Telbivudine

Purity: 98%

Molecular weight: 242.23g/mol

Ref: 54-OR1015107

Telbivudine

CAS: 3424-98-4

Formula: C₁₀H₁₄N₂O₅

Color and Shape: White To Off-White Solid

Molecular weight: 242.23

Ref: 4Z-T-251

Telbivudine

CAS: 3424-98-4

Telbivudine

Purity: ≥98%

Molecular weight: 242.23g/mol

Ref: 54-BUP15459

Telbivudine

CAS: 3424-98-4

Formula: C₁₀H₁₄N₂O₅

Purity: ≥ 99.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 242.23

Ref: 7W-GC4386

Telbivudine

CAS: 3424-98-4

Formula: C₁₀H₁₄N₂O₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 242.23

Ref: 3B-T4158

Telbivudine-d3

Controlled Product

CAS: 3424-98-4

Applications Labelled nucleoside analog; specific inhibitor of hepatitis B virus (HBV) replication. Antiviral.
References Standring, D.N., et al.: Antiviral. Chem. Chemother., 12, 119 (2001), Hernandez-Santiago, B., et al.: Antimicrob. Agents Chemother., 46, 1728 (2002), Lai, C.-L., et al.: Hepatology, 40, 719 (2004), Han, S.-H.B., et al.: Expert Opin. Invest. Drugs, 14, 511 (2005),

Formula: C₁₀H₁₁D₃N₂O₅

Color and Shape: Neat

Molecular weight: 245.25

Ref: TR-T016002

Telbivudine

Controlled Product

CAS: 3424-98-4

Applications Nucleoside analog; specific inhibitor of hepatitis B virus (HBV) replication. Antiviral.
References Standring, D.N., et al.: Antiviral. Chem. Chemother., 12, 119 (2001), Hernandez-Santiago, B., et al.: Antimicrob. Agents Chemother., 46, 1728 (2002), Lai, C.-L., et al.: Hepatology, 40, 719 (2004), Han, S.-H.B., et al.: Expert Opin. Invest. Drugs, 14, 511 (2005),

Formula: C₁₀H₁₄N₂O₅

Color and Shape: White To Off-White

Molecular weight: 242.23

Ref: TR-T016000

L-Thymidine

CAS: 3424-98-4

L-Thymidine is an antiviral drug that is used in the treatment of chronic hepatitis. It has been shown to be active against a range of viruses, including HIV, HSV, and HBV. L-Thymidine can also be used to treat patients with cancer as an anti-cancer agent. L-Thymidine is a prodrug that is converted into thymidine triphosphate (TTP), which inhibits viral DNA polymerase by competitive inhibition. The antiviral activity of L-Thymidine may be due to its ability to inhibit the synthesis of viral proteins required for viral replication by interfering with the protein production process or by inhibiting the formation of dsDNA during reverse transcription.

Formula: C₁₀H₁₄N₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 242.23 g/mol

Ref: 3D-NT02679

L-Thymidine

CAS: 3424-98-4

Formula: C₁₀H₁₄N₂O₅

Purity: 98%

Color and Shape: White powder

Molecular weight: 242.231

Ref: 10-F091804