CAS 34262-32-3

3-[(4-aminophenyl)sulfonyl]aniline

Description:

3-[(4-Aminophenyl)sulfonyl]aniline, with the CAS number 34262-32-3, is an organic compound characterized by the presence of both an aniline and a sulfonamide functional group. This compound features a sulfonyl group (-SO2-) attached to the nitrogen of an aniline ring, which contributes to its chemical reactivity and potential applications. It typically appears as a solid at room temperature and is soluble in polar solvents due to the presence of the sulfonamide group, which can engage in hydrogen bonding. The compound may exhibit properties such as moderate to high melting points and stability under standard conditions. Its structure suggests potential use in pharmaceuticals, particularly in the development of drugs targeting specific biological pathways, owing to the presence of the amino group that can participate in various chemical reactions. Additionally, the compound's sulfonamide moiety may enhance its biological activity and solubility, making it a candidate for further research in medicinal chemistry.

Formula: C₁₂H₁₂N₂O₂S

InChI: InChI=1/C12H12N2O2S/c13-9-4-6-11(7-5-9)17(15,16)12-3-1-2-10(14)8-12/h1-8H,13-14H2

SMILES: c1cc(cc(c1)S(=O)(=O)c1ccc(cc1)N)N

Synonyms:

• Benzenamine, 3-[(4-Aminophenyl)Sulfonyl]-

3-[(4-Aminophenyl)sulfonyl]benzenamine

Controlled Product

CAS: 34262-32-3

Applications 3-[(4-Aminophenyl)sulfonyl]benzenamine is an impurity of Dapsone (D193250), an antibacterial used in the treatment of dermatitis herpetiformis.
References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950); Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009); Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009);Varma, M., et al.: J. Med. Chem., 52, 4844 (2009)

Formula: C₁₂H₁₂N₂O₂S

Color and Shape: Neat

Molecular weight: 248.301

Ref: TR-A626855

3-((4-aminophenyl)sulfonyl)aniline

CAS: 34262-32-3

Formula: C₁₂H₁₂N₂O₂S

Molecular weight: 248.3

Ref: ST-EA-CP-D10019