CAS 34271-50-6

(+)-Salbutamol

Description:

(+)-Salbutamol, also known as albuterol, is a selective beta-2 adrenergic agonist primarily used as a bronchodilator in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It is characterized by its ability to relax bronchial smooth muscle, leading to improved airflow and relief from bronchospasm. The chemical structure of (+)-Salbutamol includes a phenolic hydroxyl group and a secondary amine, contributing to its pharmacological activity. It is typically administered via inhalation, oral tablets, or nebulization, with a rapid onset of action and a relatively short duration of effect. The substance is known for its stereochemistry, with the (+) enantiomer being the active form responsible for its therapeutic effects. Additionally, (+)-Salbutamol has a favorable safety profile, though potential side effects may include tremors, palpitations, and increased heart rate. Its CAS number, 34271-50-6, is a unique identifier that facilitates the identification and regulation of this compound in scientific and medical contexts.

Formula: C₁₃H₂₁NO₃

InChI: InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3/t12-/m1/s1

InChI key: InChIKey=NDAUXUAQIAJITI-GFCCVEGCSA-N

SMILES: [C@H](CNC(C)(C)C)(O)C1=CC(CO)=C(O)C=C1

Synonyms:

• (+)-Albuterol
• (+)-Salbutamol
• (S)-(+)-Salbutamol
• (S)-Albuterol
• (α¹S)-α¹-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol
• 1,3-Benzenedimethanol, α¹-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (S)-
• 1,3-Benzenedimethanol, α¹-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (α¹S)-
• 1,3-benzenedimethanol, alpha~1~-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (alpha~1~S)-
• m-Xylene-α,α′-diol, α¹-[(tert-butylamino)methyl]-4-hydroxy-, (S)-(+)-
• (α1S)-α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol
• 1,3-Benzenedimethanol, α1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (S)-
• m-Xylene-α,α′-diol, α1-[(tert-butylamino)methyl]-4-hydroxy-, (S)-(+)-

(S)-Salbutamol ((S)-Albuterol)

CAS: 34271-50-6

Formula: C₁₃H₂₁NO₃

Color and Shape: Off-White Solid

Molecular weight: 239.32

Ref: 4Z-S-1725

Salbutamol S Isomer

CAS: 34271-50-6

Formula: C₁₃H₂₁NO₃

Molecular weight: 239.31

Ref: ST-EA-CP-S7019

(S)-Albuterol Hemitartrate

Controlled Product

CAS: 34271-50-6

Applications (S)-Albuterol Hemitartrate is the S-enantiomer of Albuterol (A514500), a β2-adrenoceptor agonist. Bronchodilator; tocolytic.
References Brittain, R.T., et al.: Nature, 219, 862 (1968); Cullum, V.A, et al.: Br. J. Pharmacol. 35, 141 (1969); Martin, L.E., et al.: Eur. J. Pharmacol., 14, 183 (1971); Aboul-Enein, H.Y., Anal. Profiles Drug Subs., 10, 665 (1981)

Formula: C₁₃H₂₁NO₃(C₄H₆O₆)

Color and Shape: Neat

Molecular weight: 239.3175045

Ref: TR-A514480

S-Salbutamol

Controlled Product

CAS: 34271-50-6

Salbutamol is a bronchodilator that is used for the treatment of asthma and chronic obstructive pulmonary disease. Salbutamol is a racemic mixture of two enantiomers, R-salbutamol and S-salbutamol. The concentration–time curve for salbutamol shows an initial rapid increase in response followed by a slower, more prolonged increase. This slow phase has been attributed to the inhibition of transcription-polymerase chain reaction (PCR) activity in lung fibroblasts by S-salbutamol. Salbutamol also inhibits t-cell proliferation and induces stereoselective Ca2+ responses in lung cells.

Formula: C₁₃H₂₁NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 239.31 g/mol

Ref: 3D-FS156902

(S)-Albuterol

CAS: 34271-50-6

(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.

Formula: C₁₃H₂₁NO₃

Color and Shape: Solid

Molecular weight: 239.311

Ref: TM-T206288