CAS 342790-21-0
:L-Threonine, L-a-aspartyl-L-threonyl-L-histidyl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinylglycyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-arginyl-L-seryl-L-lysyl-L-cysteinylglycyl-L-methionyl-L-cysteinyl
Description:
The substance you are referring to, with the name "L-Threonine, L-a-aspartyl-L-threonyl-L-histidyl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-arginyl-L-seryl-L-lysyl-L-cysteinylglycyl-L-methionyl-L-cysteinyl" and CAS number "342790-21-0," is a complex peptide composed of multiple amino acids. This substance is characterized by its sequence of L-amino acids, which are the building blocks of proteins. The presence of various amino acids, including threonine, aspartic acid, histidine, phenylalanine, proline, isoleucine, cysteine, arginine, serine, lysine, and methionine, suggests that it may have diverse biological functions and potential applications in biochemistry and medicine. The peptide's structure likely influences its solubility, stability, and interaction with biological systems. Additionally, the presence of cysteine residues indicates potential for disulfide bond formation, which can affect the peptide's three-dimensional conformation and functionality. Overall, this substance may be of interest in research related to protein synthesis, enzymatic activity, and therapeutic development.
Formula:C113H170N34O31S9
Synonyms:- HepcidinHepc25 (human)
- Hepcidin-25 (human)
- Hepcidin-25
- H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-Oh
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
Hepcidin / LEAP-1
CAS:<p>Hepcidin, also known as LEAP-1 (liver-expressed antimicrobial peptide) or Hepcidin-25 is a hormone of 25 amino acids.<br>Hepcidin is a cationic, cysteine-rich and tightly folded peptide stabilized by 4 disulfide bonds that plays a major role in innate immunity and iron homeostasis.<br>Hepcidin inhibits iron transport by binding to the iron export channel ferroportin which is located on the basolateral surface of gut enterocytes and the plasma membrane of reticuloendothelial cells (macrophages). Hepcidin breaks down the transporter protein in the lysosome. Inhibiting ferroportin prevents iron exportation and iron is retained in cells.<br>Hepcidin is regulated by iron through a complex of integral hemochromatosis proteins, like HFE, HJV and transferrin receptor 2.<br>Hepcidin is also characterized by is antimicrobial activity in several vertebrate species, exerting its antimicrobial effect against both Gram-positive and Gram-negative bacteria as well as yeast, with for example an IC50 value against Saccharomyces cerevisae of 18 µM.</p>Formula:C113H170N34O31S9Purity:Min. 95%Molecular weight:2,789.4 g/molHepcidin/LEAP-1 (Human) (Bulk)
CAS:<p>Human Hepcidin peptide hormone product also know as LEAP-1 (liver-expressed antimicrobial peptide), where the disulfides are formed by random oxidation. Hepcidin is a peptide hormone that is synthesized in the liver and is an important regulator of iron homeostasis. Through binding to ferroportin Hepcidin prevents the exportation of iron thus reducing the amount of circulating iron. Furthermore through inflammatory cytokine induction Hepcidin leads to the internalization and degradation of ferroportin thus further reducing the amount of iron in circulation. This in turn make conditions unfavourable to invading pathogens. This demonstrates Hepcidin's ability as an anti-microbial peptide. This antimicrobial behaviour can be used in research into the elimination of pathogens but also in combatting diseases where iron dysregulation is prevalant.</p>Formula:C113H170N34O31S9Purity:Min. 95%Molecular weight:2,789.4 g/mol
