CAS 342790-23-2

Hepcidin-20 (human)

Description:

Hepcidin-20 is a peptide that plays a crucial role in iron metabolism and homeostasis in humans. It is a part of the hepcidin family, which is primarily produced by the liver and regulates iron absorption and distribution in the body. The peptide consists of 20 amino acids and is known for its ability to bind to ferroportin, a protein that transports iron across cell membranes, leading to the internalization and degradation of ferroportin, thereby reducing iron release into the bloodstream. This mechanism is vital for maintaining appropriate iron levels and preventing conditions such as anemia or iron overload. Hepcidin-20 is also involved in the immune response and has been studied for its potential therapeutic applications in various diseases, including anemia of chronic disease and certain infections. Its CAS number, 342790-23-2, uniquely identifies this specific peptide in chemical databases, facilitating research and development in biomedical fields. Overall, hepcidin-20 is a significant biomolecule with implications in both iron regulation and immune function.

Formula: C₈₅H₁₃₅N₂₇O₂₃S₉

Synonyms:

• Hepcidin-20 (human)

Hepcidin-20 (human)

CAS: 342790-23-2

Hepcidin-20, a degradation product of hepcidin-25 found in plasma and urine, shows an increased antimicrobial activity compared to the full-length peptide, but it is not involved in iron metabolism.

Formula: C₈₅H₁₃₅N₂₇O₂₃S₉

Purity: > 96%

Color and Shape: White Powder

Molecular weight: 2191.77

Ref: 01-4065374

Hepcidin-20 (human)

CAS: 342790-23-2

Hepcidin-20: human peptide, antifungal, hinders biofilm & bacterial metabolism in PIA+/- strains.

Formula: C₈₅H₁₃₅N₂₇O₂₃S₉

Color and Shape: Solid

Molecular weight: 2191.73

Ref: TM-T76585

Hepcidin-20 (Human)

CAS: 342790-23-2

Hepcidin-20 consists of the disulfide Bonds: Cys2-Cys18, Cys5-Cys8, Cys6-Cys14, and Cys9-Cys17 and is available in the trifluoroacetate salt form. Hepcidin-20 is a truncated form of the peptide hormone hepcidin-25, which plays a key role in the regulation of iron metabolism in the body. It is produced by the liver and is secreted into the bloodstream.
Hepcidin has the ability to regulate the activity of ferroportin, a protein that facilitates the export of iron from cells into the bloodstream. It binds to ferroportin and inhibits its activity, leading to decreased iron absorption from the diet and reduced iron release from cells.
The biological significance of hepcidin-20 is still being studied, but it may be involved in the regulation of iron metabolism in certain situations, such as inflammation or certain disease states. Like hepcidin-25, hepcidin-20 is a target for the development of treatments for iron-related disorders, such as anemia of chronic disease and hemochromatosis.

Formula: C₈₅H₁₃₅N₂₇O₂₃S₉

Purity: Min. 95%

Molecular weight: 2,191.77 g/mol

Ref: 3D-PLP-3777-PI

Hepcidin-20 (human) trifluoroacetate salt

CAS: 342790-23-2

Please enquire for more information about Hepcidin-20 (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₈₅H₁₃₅N₂₇O₂₃S₉

Purity: Min. 95%

Molecular weight: 2,191.74 g/mol

Ref: 3D-FH110066