CAS 342878-90-4

L-Valine,L-alanyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-,cyclic (2®7)-disulfide

Description:

L-Valine, L-alanyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (2®7)-disulfide, identified by CAS number 342878-90-4, is a cyclic peptide that features a unique arrangement of amino acids, including valine, alanine, cysteine, phenylalanine, tryptophan, lysine, and tyrosine. This compound is characterized by the presence of disulfide bonds, which contribute to its structural stability and biological activity. The cyclic nature of the peptide enhances its resistance to enzymatic degradation, making it potentially useful in pharmaceutical applications. The specific arrangement of amino acids can influence its interactions with biological targets, such as receptors or enzymes, thereby affecting its efficacy in various biochemical pathways. Additionally, the presence of multiple cysteine residues allows for the formation of disulfide bridges, which are crucial for maintaining the three-dimensional conformation of the peptide. Overall, this compound exemplifies the complexity and diversity of peptide structures in biochemistry, with implications for drug design and therapeutic applications.

Formula: C₄₉H₆₄N₁₀O₁₀S₂

Synonyms:

• UrotensinII-related peptide
• Urotensin II-related peptide (rat)
• Urotensin Ii-Related Peptide (Human, Mouse, Rat)

Urotensin II-Related Peptide (human, mouse, rat)

CAS: 342878-90-4

UIIIB showed high affinity to urotensin II receptors in human and rat (Kd = 170 pM and 91 pM). Furthermore, it produced a long lasting, hypotensive effect in anesthetized rats at 10 nmol/kg.

Formula: C₄₉H₆₄N₁₀O₁₀S₂

Purity: > 97%

Color and Shape: White

Molecular weight: 1017.24

Ref: 01-4043726

Urotensin II-Related Peptide (Human, Rat)

CAS: 342878-90-4

Urotensin II-related peptide (URP) is a potent, selective, nonpeptide antagonist of the calcitonin gene-related peptide receptor. URP inhibits the binding of calcitonin gene-related peptide to its receptor and blocks the effects of this peptide on a variety of cell types. In addition, URP suppresses the release of substance P from sensory neurons in rat skin and blocks neurogenic inflammation. This product is purified by HPLC and has an analytical purity of >95%.

Formula: C₄₉H₆₄N₁₀O₁₀S₂

Purity: Min. 95%

Molecular weight: 1,017.2 g/mol

Ref: 3D-PUT-4408-V

Urotensin II-Related Peptide (human, mouse, rat) trifluoroacetate salt

CAS: 342878-90-4

Urotensin II is a peptide that is expressed in the brain and has hypotensive effects. It is an endogenous ligand for the urotensin II receptor, which is found in various tissues including the heart, vascular system, and lungs. Urotensin II-Related Peptide (URP) was identified from cDNA sequences of human, mouse, and rat tissues. The URP consists of a sequence of amino acids with a molecular weight of 1219. This peptide has been shown to have diagnostic use in tissues and animals as well as being immunoreactive in monoclonal antibodies. The gene encoding URP has been cloned and its protein product has been characterized by mass spectroscopy.

Formula: C₄₉H₆₄N₁₀O₁₀S₂

Purity: Min. 95%

Molecular weight: 1,017.23 g/mol

Ref: 3D-FU109712