CAS 343-55-5

Dicloxacillin sodium

Description:

Dicloxacillin sodium is a semisynthetic penicillin antibiotic that is primarily used to treat infections caused by penicillinase-producing staphylococci. It is characterized by its ability to resist degradation by certain beta-lactamase enzymes, which makes it effective against specific strains of bacteria. The compound appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration via injection or oral formulations. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Dicloxacillin sodium is typically indicated for skin and soft tissue infections, respiratory tract infections, and osteomyelitis, among others. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, more severe reactions such as anaphylaxis. As with all antibiotics, it is essential to use dicloxacillin sodium judiciously to minimize the risk of developing antibiotic resistance.

Formula: C₁₉H₁₇Cl₂N₃O₅S·Na

InChI: InChI=1S/C19H17Cl2N3O5S.Na/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);/t13-,14+,17-;/m1./s1

InChI key: InChIKey=NTVMGKBZFMYQHI-SLINCCQESA-N

SMILES: C(O)(=O)[C@@H]1N2[C@@]([C@H](NC(=O)C=3C(=NOC3C)C4=C(Cl)C=CC=C4Cl)C2=O)(SC1(C)C)[H].[Na]

Synonyms:

• 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-
• 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, (2S-(2alpha,6beta))-
• 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-, monosodium salt
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-(2α,5α,6β)]-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1), (2S,5R,6R)-
• Brispen
• Constaphyl
• Dichlor-Stapenor
• Diclocil
• Dicloxacillin sodium anhydrous
• Dycill
• Dynapen
• Noxaben
• P 1011
• Pathocil
• Pen-Sint
• Sodium (2S-(2alpha,5alpha,6beta))-6-(((3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)carbonyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate
• Sodium (3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)penicillin
• Sodium 6-({[3-(2,6-Dichlorophenyl)-5-Methylisoxazol-4-Yl]Carbonyl}Amino)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
• Sodium dicloxacillin
• Stampen

Dicloxacillin Sodium

CAS: 343-55-5

Formula: C₁₉H₁₆Cl₂N₃NaO₅S

Purity: 97%

Color and Shape: Solid

Molecular weight: 492.3082

Ref: IN-DA00C0QP

Dicloxacillin Sodium Salt

CAS: 343-55-5

Formula: C₁₉H₁₆Cl₂N₃O₅S·Na

Color and Shape: White To Off-White Solid

Molecular weight: 469.31 22.99

Ref: 4Z-D-6810

Dicloxacillin Sodium

CAS: 343-55-5

Dicloxacillin Sodium (BRL1702 Sodium) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative bacteria.

Formula: C₁₉H₁₇Cl₂N₃O₅S·H₂O·Na

Purity: 98%

Color and Shape: Solid

Molecular weight: 510.32

Ref: TM-T6471

Dicloxacillin sodium salt

CAS: 343-55-5

Dicloxacillin is a penicillin antibiotic that is used to treat bacterial infections of the gastrointestinal tract, skin, and urinary tract. It binds to the penicillin-binding proteins in bacterial cell walls by competitive inhibition. Dicloxacillin inhibits bacterial growth by binding to the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis. Dicloxacillin sodium salt is available as tablets for oral administration or as an intravenous solution for injection. It can interact with other drugs, such as benzalkonium chloride and matrix effect; it also has analytical methods such as chromatographic analysis and rate constant.

Formula: C₁₉H₁₇Cl₂N₃O₅S·Na

Purity: Min. 95%

Molecular weight: 493.32 g/mol

Ref: 3D-AD170552