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CAS 34301-55-8

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Isometamidium chloride

Description:
Isometamidium chloride is a chemical compound primarily used as an antiparasitic agent, particularly in veterinary medicine for the treatment of trypanosomiasis in livestock. It is a member of the diamidine class of compounds, characterized by its ability to inhibit the growth of certain protozoan parasites. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in aqueous formulations. Isometamidium chloride acts by interfering with the nucleic acid metabolism of the parasites, leading to their death. Its efficacy is often attributed to its ability to penetrate the cell membranes of the parasites. While it is generally considered effective, the use of isometamidium chloride can be associated with side effects, including potential toxicity in certain animal species. As with any pharmaceutical agent, proper dosage and administration guidelines are crucial to minimize adverse effects and ensure therapeutic efficacy. Additionally, its use is regulated in many countries, reflecting the importance of responsible veterinary practices.
Formula:C28H26ClN7
InChI:InChI=1/C28H25N7.ClH/c1-2-35-26-16-20(29)11-13-24(26)23-14-12-22(17-25(23)27(35)18-7-4-3-5-8-18)33-34-32-21-10-6-9-19(15-21)28(30)31;/h3-17,29H,2H2,1H3,(H4,30,31,32,33);1H
InChI key:InChIKey=QNZJTSGALAVCLH-UHFFFAOYSA-N
SMILES:C(C)[N+]=1C(=C2C(=C3C1C=C(N)C=C3)C=CC(N=NNC4=CC(C(=N)N)=CC=C4)=C2)C5=CC=CC=C5.[Cl-]
Synonyms:
  • 3-amino-8-[(1E)-3-(3-carbamimidoylphenyl)triaz-1-en-1-yl]-5-ethyl-6-phenylphenanthridinium chloride
  • Isometamedium chloride
  • Kelamidium
  • M & B 4180A
  • M and B 4180A
  • Phenanthridinium, 3-amino-8-[3-[3-(aminoiminomethyl)phenyl]-1-triazenyl]-5-ethyl-6-phenyl-, chloride
  • Phenanthridinium, 3-amino-8-[3-[3-(aminoiminomethyl)phenyl]-2-triazen-1-yl]-5-ethyl-6-phenyl-, chloride (1:1)
  • Phenanthridinium, 8-[3-(m-amidinophenyl)-2-triazeno]-3-amino-5-ethyl-6-phenyl-, chloride
  • ISOMETAMEDIUM HCL
  • A-4180
  • See more synonyms
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