CAS 34316-15-9

Chelerythrine

Description:

Chelerythrine is a benzophenanthridine alkaloid primarily derived from various plant species, particularly those in the Papaveraceae family. It is characterized by its complex polycyclic structure, which includes a fused benzene and phenanthridine ring system. This compound exhibits a range of biological activities, including antimicrobial, anti-inflammatory, and potential anticancer properties, making it a subject of interest in pharmacological research. Chelerythrine is known to interact with various cellular targets, influencing processes such as apoptosis and cell proliferation. Its mechanism of action often involves the inhibition of protein kinases and modulation of signaling pathways. In terms of physical properties, chelerythrine is typically a yellowish crystalline solid, and it is soluble in organic solvents but has limited solubility in water. Due to its biological significance, chelerythrine is also studied for its potential therapeutic applications, although further research is needed to fully understand its efficacy and safety in clinical settings.

Formula: C₂₁H₁₈NO₄

InChI: InChI=1S/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10H,11H2,1-3H3/q+1

InChI key: InChIKey=LLEJIEBFSOEYIV-UHFFFAOYSA-N

SMILES: C[N+]=1C=2C(C=3C(C1)=C(OC)C(OC)=CC3)=CC=C4C2C=C5C(=C4)OCO5

Synonyms:

• 1,2-Dimethoxy-12-Methyl[1,3]Benzodioxolo[5,6-C]Phenanthridin-12-Ium
• Broussonpapyrine
• Cheleritrine
• Chelerythrine
• Chelerythrine chloride
• Toddalin
• Toddaline
• [1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-
• 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium
• 1,2-Dimethoxy-12-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium
• 1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
• CHELERYTHRINE(TODDALINE)(RG)

[1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-

CAS: 34316-15-9

Formula: C₂₁H₁₈NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 348.3719

Ref: IN-DA00IKL1

Chelerythrine

CAS: 34316-15-9

Chelerythrine

Purity: ≥98%

Molecular weight: 348.37g/mol

Ref: 54-BUP06361

Chelerythrine

CAS: 34316-15-9

Formula: C₂₁H₁₈NO₄

Purity: ≥ 98.0%

Color and Shape: White to yellow powder

Molecular weight: 348.37

Ref: 7W-GP0942

Chelerythrine

CAS: 34316-15-9

Formula: C₂₁H₁₈NO₄

Purity: 95%~99%

Molecular weight: 348.377

Ref: BP-BP0340

Chelerythrine

CAS: 34316-15-9

1.

Formula: C₂₁H₁₈NO₄

Purity: 98.36%

Color and Shape: Solid

Molecular weight: 348.37

Ref: TM-T6S0052

Chelerythrine

CAS: 34316-15-9

Chelerythrine is a natural benzophenanthridine alkaloid, which is isolated from plants in the Papaveraceae family. This compound is primarily known for its role as a potent inhibitor of protein kinase C (PKC), an enzyme critical in various cellular signaling pathways. Chelerythrine exhibits its mode of action by competitively binding to the ATP-binding site of PKC, thereby inhibiting its activity. This inhibition disrupts downstream signaling processes involved in cell proliferation, differentiation, and apoptosis.

Formula: C₂₁H₁₈NO₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 348.37 g/mol

Ref: 3D-FC73805