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CAS 34346-01-5

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Poly(lactic-co-glycolic acid)

Description:
Poly(lactic-co-glycolic acid) (PLGA) is a biodegradable copolymer composed of lactic acid and glycolic acid monomers. It is characterized by its biocompatibility, making it suitable for various biomedical applications, including drug delivery systems, tissue engineering, and sutures. PLGA's properties can be tailored by adjusting the ratio of lactic to glycolic acid, which influences its degradation rate and mechanical strength. Typically, PLGA exhibits a glass transition temperature that allows it to remain flexible at physiological temperatures. The degradation of PLGA occurs through hydrolysis, leading to the gradual release of the encapsulated drugs or the breakdown of the polymer into non-toxic byproducts, primarily lactic and glycolic acids, which are naturally metabolized by the body. Additionally, PLGA can be processed into various forms, such as microspheres, films, and scaffolds, enhancing its versatility in medical applications. Its FDA approval for use in medical devices further underscores its safety and efficacy in clinical settings.
Formula:(C3H6O3·C2H4O3)x
InChI:InChI=1S/C3H6O3.C2H4O3/c1-2(4)3(5)6;3-1-2(4)5/h2,4H,1H3,(H,5,6);3H,1H2,(H,4,5)
InChI key:InChIKey=XBBVURRQGJPTHH-UHFFFAOYSA-N
SMILES:C(CO)(O)=O.C(C(O)=O)(C)O
Synonyms:
  • (.+-.)-2-Hydroxypropanoic acid-hydroxyacetic acid copolymer
  • 2-Hydroxyacetic acid-lactic acid copolymer
  • 85Dg065
  • <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Lactic acid-glycolic acid copolymer
  • Acetic acid, hydroxy-, polymer with 2-hydroxypropanoic acid
  • Alzamer Depot
  • B 6006-1P
  • Expansorb DLG 50-2A
  • GC-Membrane
  • Glycolic acid-<span class="text-smallcaps">D</smallcap><smallcap>L</span>-lactic acid copolymer
  • See more synonyms
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Found 4 products.
  • CymitQuimica logo
    USP
    + Info

    PLGA 75:25 DLLAGA 2A (Poly(DL-lactic acid-co-glycolic acid) acid terminated (75:25))

    CAS:
    Polyesters, saturated, in primary forms, nesoi
    Formula:HC3H4O2nC2H2O2mOH
    Color and Shape:White Powder
    Molecular weight:4.000-15.000 Da

    Ref: 45-1800101

  • PLGA
    Targetmol
    + Info

    PLGA

    CAS:
    PLGA (poly(lactic-co-glycolic acid)) is be used to fabricate devices for drug delivery and tissue engineering applications.
    Formula:(C3H6O3·C2H4O3)x
    Purity:50:50 - 50:50
    Color and Shape:Solid
    Molecular weight:166.129

    Ref: TM-T19521

    200mg
    39.00€
  • PLGA
    Biosynth
    + Info

    PLGA

    CAS:
    PLGA is a biocompatible polymer that is used in the manufacture of implantable medical devices. It is also used as an injection solution and has significant cytotoxicity. PLGA has been shown to be effective in vivo in animal models with breast cancer, hypoglycemia, and bone-disease implants. In vitro studies have confirmed its efficacy as a delivery vehicle for growth factor-β1. Furthermore, PLGA nanoparticles are being investigated as a drug-delivery system for radiation therapy.
    Formula:(C3H6O3)n•(C2H4O3)n
    Purity:Min 98%
    Color and Shape:Powder

    Ref: 3D-FP166703

    2g
    410.00€
    5g
    607.00€
    10g
    863.00€
    25g
    1,356.00€
    50g
    2,113.00€
  • PLGA(50:50)
    Biosynth
    + Info

    PLGA(50:50)

    CAS:
    <p>Please enquire for more information about PLGA(50:50) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formula:(C3H6O3•C2H4O3)x

    Ref: 3D-FP184493

    25g
    668.00€
    50g
    978.00€
    100g
    1,410.00€
    250g
    2,639.00€
    500g
    4,754.00€