CAS 3436-44-0

Didecanoylphosphatidylcholine

Description:

Didecanoylphosphatidylcholine, also known as di-C10-PC, is a synthetic phospholipid that belongs to the class of phosphatidylcholines. It is characterized by its two decanoyl (C10) fatty acid chains attached to a glycerol backbone, along with a phosphate group linked to a choline moiety. This structure imparts amphiphilic properties, allowing it to form bilayers and micelles in aqueous environments, which is crucial for its role in biological membranes and drug delivery systems. Didecanoylphosphatidylcholine is typically used in research and industrial applications, particularly in the formulation of liposomes and as a model membrane system for studying membrane dynamics and interactions. Its hydrophobic tails contribute to membrane stability, while the hydrophilic head group facilitates interactions with aqueous environments. Additionally, it is important in the study of membrane fluidity and permeability, making it a valuable compound in biochemistry and pharmaceutical research. Safety and handling precautions should be observed, as with all chemical substances, to ensure proper laboratory practices.

Formula: C₂₈H₅₆NO₈P

InChI: InChI=1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3/t26-/m1/s1

InChI key: InChIKey=MLKLDGSYMHFAOC-AREMUKBSSA-N

SMILES: [C@H](COP(OCC[N+](C)(C)C)(=O)[O-])(COC(CCCCCCCCC)=O)OC(CCCCCCCCC)=O

Synonyms:

• (2R)-2,3-bis(decanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
• (R)-2,3-Bis(decanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
• 1,2-Didecanoyl-sn-glycero-3-phosphocholine
• 3,5,9-Trioxa-4-phosphanonadecan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxodecyl)oxy]-, inner salt, 4-oxide, (7R)-
• 3,5,9-Trioxa-4-phosphanonadecan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxodecyl)oxy]-, inner salt, 4-oxide, (R)-
• <span class="text-smallcaps">L</span>-Dicapryllecithin
• <span class="text-smallcaps">L</span>-Didecanoyllecithin
• <span class="text-smallcaps">L</span>-Didecanoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-α-Didecanoylphosphatidylcholine
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-didecanoin, <span class="text-smallcaps">L</span>-
• Coatsome MC 1010
• Decanoin, 1,2-di-, dihydrogen phosphate, monoester with choline hydroxide inner salt, <span class="text-smallcaps">L</span>-
• Didecanoyl-<span class="text-smallcaps">L</span>-α-glycerophosphorylcholine
• Didecanoyl-<span class="text-smallcaps">L</span>-α-phosphatidycholine
• Didecanoylglycerophosphocholine
• Didecanoyllecithin
• Didecanoylphosphatidylcholine
• L-a-Lecithin-dicaproyl = L-a-Dicaproyl Lecithin = L-a-Dicapryl Lecithin = L-a-Dicaprylyl Lecithin
• Pc(10:0/10:10)
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-didecanoin, L-
• L-Dicapryllecithin

1,2-didecanoyl-sn-glycero-3-phosphocholine

CAS: 3436-44-0

Formula: C₂₈H₅₆NO₈P

Purity: 95%

Color and Shape: Solid

Molecular weight: 565.7199

Ref: IN-DA00BYUO

(R)-2,3-Bis(decanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

CAS: 3436-44-0

(R)-2,3-Bis(decanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

Purity: 95%

Molecular weight: 565.73g/mol

Ref: 54-OR1070860

1,2-Didecanoyl-sn-glycero-3-phosphocholi

CAS: 3436-44-0

1,2-Didecanoyl PC: synthetic phospholipid aiding peptide drug and insulin absorption.

Formula: C₂₈H₅₆NO₈P

Purity: 98%

Color and Shape: Solid

Molecular weight: 565.72

Ref: TM-T4949

1,2-Didecanoyl-sn-glycero-3-phosphocholine

CAS: 3436-44-0

1,2-Didecanoyl-sn-glycero-3-phosphocholine (DDPC) is a phospholipid that is used as an absorption enhancer. DDPC has been shown to have inhibitory effects on propranolol hydrochloride and p-glycoprotein (Pgp). It binds to the Pgp substrate site and blocks the transport of drugs in the cell membrane. This drug is also a model system for studying the hydrophobic effect of phospholipids. The phase transition temperature for DDPC is about 40°C, which indicates its hydrophilic nature. The acyl chain length of this lipid determines its phase transition temperature at different temperatures.

Formula: C₂₈H₅₆NO₈P

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 565.72 g/mol

Ref: 3D-DAA43644

1,2-Didecanoyl PC

Controlled Product

CAS: 3436-44-0

Formula: C₂₈H₅₆NO₈P

Color and Shape: Neat

Molecular weight: 565.72

Ref: TR-D439318