CAS 34385-94-9

5-Chloro-2,3-dihydro-2-benzofurancarboxylic acid

Description:

5-Chloro-2,3-dihydro-2-benzofurancarboxylic acid is an organic compound characterized by its unique bicyclic structure, which includes a benzofuran moiety. The presence of a chlorine atom at the 5-position and a carboxylic acid functional group contributes to its chemical reactivity and potential applications. This compound typically exhibits moderate solubility in polar solvents due to the carboxylic acid group, while its aromatic structure may impart some hydrophobic characteristics. The compound's molecular structure suggests it may participate in various chemical reactions, such as nucleophilic substitutions or coupling reactions, making it of interest in synthetic organic chemistry. Additionally, its derivatives may have biological activity, which could be explored for pharmaceutical applications. Safety data indicates that, like many chlorinated compounds, it should be handled with care due to potential toxicity. Overall, 5-Chloro-2,3-dihydro-2-benzofurancarboxylic acid represents a versatile building block in organic synthesis and medicinal chemistry.

Formula: C₉H₇ClO₃

InChI: InChI=1S/C9H7ClO3/c10-6-1-2-7-5(3-6)4-8(13-7)9(11)12/h1-3,8H,4H2,(H,11,12)

InChI key: InChIKey=DVOUUBIBLOOFKC-UHFFFAOYSA-N

SMILES: C(O)(=O)C1OC=2C(C1)=CC(Cl)=CC2

Synonyms:

• (2R)-5-chloro-2,3-dihydro-1-benzofuran-2-carboxylate
• (2S)-5-chloro-2,3-dihydro-1-benzofuran-2-carboxylate
• (±)-5-Chloro-2,3-dihydro-2-benzofurancarboxylic acid
• 2-Benzofurancarboxylic Acid, 5-Chloro-2,3-Dihydro-
• 5-Chloro-2,3-dihydrocoumarilic acid
• 5-Chloro-2,3-dihydro-1-benzofuran-2-carboxylic acid

5-Chloro-2,3-dihydro-benzofuran-2-carboxylic acid

CAS: 34385-94-9

Formula: C₉H₇ClO₃

Purity: %

Molecular weight: 198.6031

Ref: IN-DA00CLT9

5-Chloro-2,3-dihydro-benzofuran-2-carboxylic acid

CAS: 34385-94-9

5-Chloro-2,3-dihydro-benzofuran-2-carboxylic acid

Purity: 95%

Molecular weight: 198.60g/mol

Ref: 54-OR953943

5-Chloro-2,3-dihydrobenzofuran-2-carboxylic acid

CAS: 34385-94-9

5-Chloro-2,3-dihydrobenzofuran-2-carboxylic acid is a hypocholesterolemic agent that has been shown to lower plasma cholesterol levels in the rat model. This compound is an analog of propionate, a known hypocholesterolemic agent. 5-Chloro-2,3-dihydrobenzofuran-2-carboxylic acid is converted by esterases to its active form, 1,4-benzoquinone dioxane 2 carboxylic acid (BQDCA). The structural similarity of BQDCA with propionate suggests that it may have similar biological activities. 5-Chloro-2,3-dihydrobenzofuran-2-carboxylic acid also possesses some antihyperlipemic activity and has been shown to inhibit the synthesis of triglycerides in rat liver cells.

Formula: C₉H₇ClO₃

Purity: Min. 95%

Molecular weight: 198.6 g/mol

Ref: 3D-JBA38594