CAS 34391-04-3
:(-)-Salbutamol
Description:
(-)-Salbutamol, also known as albuterol, is a selective beta-2 adrenergic agonist primarily used as a bronchodilator in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It is characterized by its ability to relax bronchial smooth muscle, leading to dilation of the airways and improved airflow. The compound has a chiral center, and the (-)-enantiomer is the active form responsible for its therapeutic effects. Chemically, it is classified as a phenolic compound with a structure that includes a catechol moiety and a tertiary butyl group, contributing to its lipophilicity and receptor selectivity. (-)-Salbutamol is typically administered via inhalation, allowing for rapid onset of action and reduced systemic side effects. Its pharmacokinetics include a relatively short half-life, necessitating multiple doses for sustained effect. Common side effects may include tremors, palpitations, and headaches, which are generally mild. Overall, (-)-Salbutamol is a crucial medication in respiratory therapy, providing relief for individuals with obstructive airway diseases.
Formula:C13H21NO3
InChI:InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3/t12-/m0/s1
InChI key:InChIKey=NDAUXUAQIAJITI-LBPRGKRZSA-N
SMILES:[C@@H](CNC(C)(C)C)(O)C1=CC(CO)=C(O)C=C1
Synonyms:- (L)-Albuterol
- (R)-(-)-Salbutamol
- (R)-Albuterol
- (α<sup>1</sup>R)-α<sup>1</sup>-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol
- 1,3-Benzenedimethanol, α<sup>1</sup>-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (R)-
- 1,3-Benzenedimethanol, α<sup>1</sup>-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (α<sup>1</sup>R)-
- 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol
- 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol hydrochloride (1:1)
- 4-[2-(Tert-Butylamino)-1-Hydroxyethyl]-2-(Hydroxymethyl)Phenol
- Albuterol
- Asf 1096
- Levalbuterol
- Levosalbutamol
- Salbutamol
- m-Xylene-α,α′-diol, α<sup>1</sup>-[(tert-butylamino)methyl]-4-hydroxy-, (R)-(-)-
- m-Xylene-α,α′-diol, α1-[(tert-butylamino)methyl]-4-hydroxy-, (R)-(-)-
- 1,3-Benzenedimethanol, α1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (R)-
- 1,3-Benzenedimethanol, α1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (α1R)-
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