CAS 344-80-9

(2-Amino-5-nitrophenyl)(2-fluorophenyl)methanone

Description:

(2-Amino-5-nitrophenyl)(2-fluorophenyl)methanone, with the CAS number 344-80-9, is an organic compound characterized by its complex structure, which includes an amino group, a nitro group, and a ketone functional group. This compound typically appears as a solid at room temperature and is soluble in organic solvents. The presence of the amino group contributes to its potential as a building block in pharmaceuticals and agrochemicals, while the nitro group can impart unique reactivity and properties, such as increased electron-withdrawing characteristics. The fluorine atom in the 2-fluorophenyl moiety enhances the compound's lipophilicity and can influence its biological activity. Overall, this compound is of interest in synthetic organic chemistry and medicinal chemistry due to its potential applications in drug development and as a precursor for further chemical modifications. Safety data should be consulted for handling and storage, as compounds with nitro and amino groups can exhibit varying degrees of toxicity and reactivity.

Formula: C₁₃H₉FN₂O₃

InChI: InChI=1S/C13H9FN2O3/c14-11-4-2-1-3-9(11)13(17)10-7-8(16(18)19)5-6-12(10)15/h1-7H,15H2

InChI key: InChIKey=ZTEHQPVGEHUXHI-UHFFFAOYSA-N

SMILES: C(=O)(C1=CC(N(=O)=O)=CC=C1N)C2=C(F)C=CC=C2

Synonyms:

• (2-Amino-5-Nitro-Phenyl)-(2-Fluoro-Phenyl)-Methanone
• (2-Amino-5-nitrophenyl)(2-fluorophenyl)methanone
• 2-Amino-2'-fluoro-5-Nitryl-diphenylmethanone
• 2-Amino-5-nitro-2'-fluorobenzophenone
• 2-Amino-5-nitrophenyl(2-fluorophenyl) ketone
• Benzophenone, 2-amino-2′-fluoro-5-nitro-
• Methanone, (2-amino-5-nitrophenyl)(2-fluorophenyl)-
• 2-Amino-2′-fluoro-5-nitrobenzophenone

(2-Amino-5-nitrophenyl)(2-fluorophenyl)methanone

CAS: 344-80-9

Formula: C₁₃H₉FN₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 260.2206

Ref: IN-DA007FI7

2-Amino-2'-fluoro-5-nitrobenzophenone

CAS: 344-80-9

2-Amino-2'-fluoro-5-nitrobenzophenone

Purity: 98%

Molecular weight: 260.22g/mol

Ref: 54-PC1371

2-Amino-5-nitro-2'-fluorobenzophenone

CAS: 344-80-9

Applications Intermediate in the production of Flunitrazepam metabolites.
References Stafford, J., et al.: Bioorg. Med. Chem. Lett., 12, 3215 (2002),

Formula: C₁₃H₉FN₂O₃

Color and Shape: Neat

Molecular weight: 260.22

Ref: TR-A618420

2-Amino-5-nitro-2'-fluorobenzophenone

CAS: 344-80-9

2-Amino-5-nitro-2'-fluorobenzophenone is a prodrug that is activated by thiourea, a chemical agent that is used to break down the drug. It is an anti-inflammatory drug that acts as a selective COX inhibitor and has been shown to be effective in vivo against primary tumors. 2-Amino-5-nitro-2'-fluorobenzophenone has also been shown to have antiangiogenic properties and has been used to treat inflammatory diseases such as arthritis and psoriasis. This drug can be radiolabeled with carbon, fluorine, or iodine isotopes for use in positron emission tomography (PET) imaging of primary tumors. The drug binds to response elements on cells through electrostatic interactions between the molecular orbitals of the 2 amino groups and the nucleophilic centers of these molecules.

Formula: C₁₃H₉FN₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 260.22 g/mol

Ref: 3D-FA17637

2-Amino-2′-fluoro-5-nitrobenzophenone

CAS: 344-80-9

Formula: C₁₃H₉FN₂O₃

Purity: 97%

Color and Shape: Liquid, No data available.

Molecular weight: 260.224

Ref: 10-F216397