CAS 344458-15-7

N~2~,N~2~-dimethyl-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)glycinamide hydrochloride

Description:

N~2~,N~2~-dimethyl-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)glycinamide hydrochloride is a chemical compound characterized by its complex structure, which includes a phenanthridine moiety and a glycinamide functional group. This substance is typically a white to off-white solid and is soluble in polar solvents, which is common for many amides and hydrochloride salts. The presence of the dimethyl and phenanthridine groups suggests potential biological activity, possibly as a pharmaceutical agent. Its hydrochloride form indicates that it is a salt, which often enhances solubility and stability. The compound may exhibit specific interactions with biological targets, making it of interest in medicinal chemistry. As with many chemical substances, handling should be done with care, following appropriate safety protocols, as it may have specific toxicity or reactivity profiles. Further studies would be necessary to fully elucidate its properties, including its pharmacokinetics, mechanism of action, and potential therapeutic applications.

Formula: C₁₇H₁₇N₃O₂·HCl

Synonyms:

• Pj34
• Pj-34 Hcl

PJ34 HCl

CAS: 344458-15-7

Formula: C₁₇H₁₈ClN₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 331.7967

Ref: IN-DA00C6HC

PJ34 hydrochloride

CAS: 344458-15-7

PJ34 hydrochloride

Purity: ≥95%

Molecular weight: 331.8g/mol

Ref: 54-BUP15706

PJ34 hydrochloride

CAS: 344458-15-7

PJ34 hydrochloride

Purity: 98%

Molecular weight: 331.80g/mol

Ref: 54-OR1014675

PJ34 hydrochloride

CAS: 344458-15-7

PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.

Formula: C₁₇H₁₈ClN₃O₂

Purity: 98.87% - ≥95%

Color and Shape: Solid

Molecular weight: 331.8

Ref: TM-T2124

PJ-34 hydrochloride hydrate

CAS: 344458-15-7

Formula: C₁₇H₁₇N₃O₂HCl

Molecular weight: 331.80

Ref: 7W-GL7437

2-(Dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetamide hydrochloride

CAS: 344458-15-7

Purity: 95.0%

Molecular weight: 331.79998779296875

Ref: 10-F322623

PJ 34 Hydrochloride

Controlled Product

CAS: 344458-15-7

Formula: C₁₇H₁₆N₂O₂·HCl

Color and Shape: Neat

Molecular weight: 316.782

Ref: TR-P570500

PJ 34 hydrochloride

CAS: 344458-15-7

PJ 34 hydrochloride is a platinum-based anti-cancer drug that is used to treat solid tumours in combination with other chemotherapeutic drugs. It has been shown to have a protective effect on cisplatin-induced nephrotoxicity in vitro and in vivo, by modulating the acetylation of proteins, which leads to the inhibition of DNA methyltransferase activity. PJ 34 hydrochloride has also been shown to inhibit cancer cell growth and induce necrotic cell death. This drug also has genotoxic effects, as it can cause oxidative damage to DNA, which may lead to carcinogenic changes. PJ 34 hydrochloride is an inhibitor of CDK4/6 proteins and is effective at doses between 0.1-1 µM.

Formula: C₁₇H₁₈ClN₃O₂

Purity: Min. 95%

Molecular weight: 331.8 g/mol

Ref: 3D-FP27097