CAS 344458-19-1

Acetamide, N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)-

Description:

Acetamide, N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)-, identified by CAS number 344458-19-1, is a chemical compound that features a phenanthridine core structure, which is a fused polycyclic aromatic system. This compound contains an acetamide functional group, contributing to its potential as a bioactive molecule. The presence of a dimethylamino group suggests that it may exhibit basic properties, influencing its solubility and reactivity. The 5,6-dihydro-6-oxo moiety indicates that it has a ketone functional group, which can participate in various chemical reactions, including nucleophilic attacks. This compound may be of interest in medicinal chemistry due to its structural features, which could impart specific biological activities. Its characteristics, such as melting point, boiling point, solubility, and stability, would depend on the specific conditions and environment in which it is studied. Overall, this compound's unique structure may provide avenues for research in pharmacology and organic synthesis.

Formula: C₁₇H₁₇N₃O₂

Acetamide, N-(5,6-dihydro-6-oxo-2-phenanthridinyl)-2-(dimethylamino)-

CAS: 344458-19-1

Formula: C₁₇H₁₇N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 295.3358

Ref: IN-DA007FIT

PJ34

CAS: 344458-19-1

PJ34

Purity: ≥95%

Molecular weight: 295.34g/mol

Ref: 54-BUP06930

PJ34

CAS: 344458-19-1

PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.

Formula: C₁₇H₁₇N₃O₂

Purity: 95.05% - 99.85%

Color and Shape: Solid

Molecular weight: 295.34

Ref: TM-T6197

PJ34

CAS: 344458-19-1

PJ34 is a chemical compound that induces apoptosis in cancer cells. It has been shown to induce caspase-independent cell death in myeloma cells and HL-60 leukemia cells, but not in normal cells. PJ34 is a selective inhibitor of PARP-1, an enzyme that regulates the balance between DNA repair and apoptosis. This drug also induces neuronal death by inhibiting basic proteins without inducing necrosis.

Formula: C₁₇H₁₇N₃O₂

Purity: Min. 95%

Molecular weight: 295.34 g/mol

Ref: 3D-UNA45819