CAS 34450-16-3

N1-Acetylspermidine dihydrochloride

Description:

N1-Acetylspermidine dihydrochloride is a chemical compound that serves as a derivative of spermidine, an important polyamine involved in cellular functions such as growth and differentiation. This compound is characterized by the presence of an acetyl group attached to the nitrogen atom at the first position of the spermidine backbone, which enhances its solubility and biological activity. It typically appears as a white to off-white crystalline powder and is soluble in water due to the presence of dihydrochloride salts. N1-Acetylspermidine is of interest in biochemical research, particularly in studies related to cell proliferation, apoptosis, and the regulation of gene expression. Its role in cellular metabolism and potential implications in cancer research make it a subject of ongoing investigation. As with many chemical substances, proper handling and storage are essential to maintain its stability and efficacy, and safety data sheets should be consulted for information regarding toxicity and safe usage.

Formula: C₉H₂₁N₃O·2ClH

InChI: InChI=1S/C9H21N3O.2ClH/c1-9(13)12-8-4-7-11-6-3-2-5-10;;/h11H,2-8,10H2,1H3,(H,12,13);2*1H

InChI key: InChIKey=IVLOLMVLUOGVCZ-UHFFFAOYSA-N

SMILES: C(NCCCCN)CCNC(C)=O.Cl

Synonyms:

• Acetamide, N-[3-[(4-aminobutyl)amino]propyl]-, dihydrochloride
• Acetamide, N-[3-[(4-aminobutyl)amino]propyl]-, hydrochloride (1:2)
• N1-Acetylspermidine dihydrochloride

N(sup 1)-acetylspermidine dihydrochloride

CAS: 34450-16-3

Formula: C₉H₂₃Cl₂N₃O

Purity: 95%

Color and Shape: Solid

Molecular weight: 260.2044

Ref: IN-DA00C9F2

N-(3-((4-Aminobutyl)Amino)Propyl)Acetamide Dihydrochloride

CAS: 34450-16-3

N-(3-((4-Aminobutyl)Amino)Propyl)Acetamide Dihydrochloride

Purity: 95%

Molecular weight: 260.2g/mol

Ref: 54-OR1023958

N1-Acetylspermidine hydrochloride

CAS: 34450-16-3

N1-Acetylspermidine hydrochloride

Purity: ≥98%

Molecular weight: 260.2g/mol

Ref: 54-BUP02855

N1-Acetylspermidine-d6 Dihydrochloride

Controlled Product

CAS: 34450-16-3

Applications Labelled Dihydrochloride salt of N1-Acetylspermidine which is an analog of Spermidine (S680400), an antineoplastic.
References Bergeron, R. et al.: J. Med. Chem, 40, 1475 (1997);

Formula: C₉H₁₇D₆Cl₂N₃O

Color and Shape: Neat

Molecular weight: 266.24

Ref: TR-A187847

N1-Acetylspermidine-d3 Dihydrochloride

Controlled Product

CAS: 34450-16-3

Applications N1-Acetylspermidine-d3 Dihydrochloride is the isotope labelled analog of N1-Acetylspermidine Dihydrochloride (A187845); an analog of Spermidine (S680400) which is an antineoplastic.
References Bergeron, R. et al.: J. Med. Chem, 40, 1475 (1997)

Formula: C₉D₃H₁₈N₃O·2HCl

Color and Shape: Neat

Molecular weight: 263.223

Ref: TR-A187848

N1-Acetylspermidine hydrochloride

CAS: 34450-16-3

N1-Acetylspermidine HCl, an acetyl spermidine derivative, boosts polyamine oxidase levels in colorectal adenocarcinomas.

Formula: C₉H₂₃Cl₂N₃O

Purity: 99.76%

Color and Shape: Solid

Molecular weight: 260.2

Ref: TM-T37170

N1- Acetylspermidine Dihydrochloride

CAS: 34450-16-3

Applications Dihydrochloride salt of N1-Acetylspermidine which is an analog of Spermidine (S680400), an antineoplastic.
References Bergeron, R. et al.: J. Med. Chem, 40, 1475 (1997);

Formula: C₉H₂₁N₃O·2ClH

Color and Shape: Off-White

Molecular weight: 260.20

Ref: TR-A187845

N(sup 1)-acetylspermidine dihydrochloride

CAS: 34450-16-3

Purity: ≥95%

Molecular weight: 260.2000122

Ref: 10-F863487

N1-Acetylspermidine dihydrochloride

CAS: 34450-16-3

N-Acetylspermidine dihydrochloride is a polyamine oxidase inhibitor that has been shown to be useful in the treatment of cancer. It inhibits the synthesis of ornithine and N-acetylornithine, which are intermediates in polyamine biosynthesis. Inhibition of polyamine biosynthesis may lead to a decrease in cellular proliferation and an increase in apoptosis. The effect of this drug on human tissues has been studied using high performance liquid chromatography (HPLC). This drug also inhibits the activity of human urine decarboxylase, leading to a decrease in urinary excretion of ornithine and increased urinary excretion of putrescine.

Formula: C₉H₂₃Cl₂N₃O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 260.2 g/mol

Ref: 3D-FA45725