CAS 3447-95-8

Benfurodil hemisuccinate

Description:

Benfurodil hemisuccinate is a chemical compound that serves primarily as a pharmaceutical agent. It is derived from benfurodil, which is known for its vasodilatory properties, often utilized in the treatment of peripheral vascular disorders. The hemisuccinate form indicates that the compound is a derivative where a succinic acid moiety is esterified to benfurodil, enhancing its solubility and bioavailability. This modification can influence its pharmacokinetic properties, making it more effective in therapeutic applications. Benfurodil itself acts as an antagonist of certain receptors, contributing to its ability to improve blood flow and reduce symptoms associated with ischemic conditions. The compound is typically characterized by its molecular structure, which includes a furodil core, and its solubility in various solvents, which is crucial for formulation in pharmaceutical preparations. Safety and efficacy profiles are established through clinical studies, and like many pharmaceuticals, it may have specific side effects and contraindications that need to be considered in its use.

Formula: C₁₉H₁₈O₇

InChI: InChI=1S/C19H18O7/c1-10-14-7-12(13-8-18(23)24-9-13)3-4-15(14)26-19(10)11(2)25-17(22)6-5-16(20)21/h3-4,7-8,11H,5-6,9H2,1-2H3,(H,20,21)

InChI key: InChIKey=URIZBPYQIRFMBF-UHFFFAOYSA-N

SMILES: CC=1C=2C(OC1C(OC(CCC(O)=O)=O)C)=CC=C(C2)C=3COC(=O)C3

Synonyms:

• (Succinyloxy-1 ethyl)-2 methyl-3 (oxo-2 dihydro-2,5 furyl-4)-5 benzo(6)furanne
• (Succinyloxy-1 ethyl)-2 methyl-3 (oxo-2 dihydro-2,5 furyl-4)-5 benzo(6)furanne [French]
• 2-(1-(Succinoyloxy)ethyl)-3-methyl-5-(2-oxo-2,5-dihydro-4-furyl)benzo(b)furan
• 2-(1-Hydroxyethyl)-beta-(hydroxymethyl)-3-methyl-5-benzofuranacrylic acid gamma-lactone hydrogen succinate
• 2-(1-Succinyloxyethyl)-3-methyl-5-(2-oxo-2,5-dihydro-4-furyl)benzo(b)furan
• 4-{1-[3-Methyl-5-(5-Oxo-2,5-Dihydrofuran-3-Yl)-1-Benzofuran-2-Yl]Ethoxy}-4-Oxobutanoic Acid
• 4091Cb
• Benfurodil hemisuccinate [INN:DCF]
• Benfurodil hemisuccinato
• Benfurodil hemisuccinato [Spanish]
• Benfurodili hemisuccinas
• Benfurodili hemisuccinas [INN-Latin]
• Benfurodili succinas
• Benzofurodil
• Butanedioic acid, 1-[1-[5-(2,5-dihydro-5-oxo-3-furanyl)-3-methyl-2-benzofuranyl]ethyl] ester
• Butanedioic acid, mono[1-[5-(2,5-dihydro-5-oxo-3-furanyl)-3-methyl-2-benzofuranyl]ethyl] ester
• Cb 4091
• Eucilat
• Eudilat
• Hemisuccinate de benfurodil
• Hemisuccinate de benfurodil [INN-French]
• Succinic acid, ester with 2-(1-hydroxyethyl)-β-(hydroxymethyl)-3-methyl-5-benzofuranacrylic acid γ-lactone
• Succinic acid, monoester with 4-(2-(1-hydroxyethyl)-3-methyl-5-benzofuranyl)-2(5H)-furanone
• Unii-Y4Z8D13662
• Benfurodil hemisuccinate

Benzofurodil

CAS: 3447-95-8

Benzofurodil is a research tool that can be used to activate, bind and block ligand-gated ion channels. It also binds to the receptor site of certain proteins and blocks the effects of peptides, which are small protein molecules. Benzofurodil is a high purity compound with a CAS number of 3447-95-8. Benzofurodil has been shown to inhibit the activity of ion channels by binding to the amino acid residues in the channel pore. The compound has also been shown to block the binding of some neurotransmitters in neurons and muscle cells, which may help control seizures, anxiety and other neurological disorders.

Formula: C₁₉H₁₈O₇

Purity: Min. 95%

Molecular weight: 358.3 g/mol

Ref: 3D-DAA44795

Benzofurodil

CAS: 3447-95-8

Benzofurodil is cardiotonic used for the chronic treatment of congestive heart failure.

Formula: C₁₉H₁₈O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 358.34

Ref: TM-T13599