CAS 34535-42-7

1H,2H,3H-Pyrrolo[3,4-b]quinolin-3-one

CAS: 34535-42-7

1H,2H,3H-Pyrrolo[3,4-b]quinolin-3-one is a natural product that inhibits the growth of cancer cells. It has been shown to be cytotoxic against human breast cancer cells in vitro and in vivo. The mechanism of action of this compound is not known but it has been shown to inhibit the growth of human breast cancer cells by deprotonation of a chloride anion. This compound may also be related to the anthranilic acid class of compounds and is an alkaloid with a bicyclic structure. 1H,2H,3H-Pyrrolo[3,4-b]quinolin-3-one is synthesized by cyclocondensation from luotonin and microwave irradiation. It can be obtained in high yields from anthranilic acid under alkaline conditions. Irradiation with microwaves is also used for its synthesis which produces unambiguous results.

Formula: C₁₁H₈N₂O

Purity: Min. 95%

Molecular weight: 184.19 g/mol

Ref: 3D-JBA53542