CAS 34540-22-2

Madecassoside

Description:

Madecassoside is a triterpenoid saponin derived from the Centella asiatica plant, commonly known for its medicinal properties. It is characterized by its anti-inflammatory, antioxidant, and wound-healing effects, making it a popular ingredient in skincare formulations. The compound exhibits a complex molecular structure, which contributes to its biological activities. Madecassoside is soluble in water and organic solvents, allowing for versatile applications in both pharmaceutical and cosmetic industries. Its mechanism of action involves the modulation of various signaling pathways, promoting collagen synthesis and enhancing skin barrier function. Additionally, madecassoside has been studied for its potential neuroprotective effects and its ability to improve skin hydration and elasticity. Due to its natural origin and beneficial properties, it is often favored in formulations aimed at soothing irritated skin and promoting overall skin health. Overall, madecassoside is recognized for its therapeutic potential and is increasingly utilized in various health and beauty products.

Formula: C₄₈H₇₈O₂₀

InChI: InChI=1S/C48H78O20/c1-19-10-11-48(13-12-46(6)22(28(48)20(19)2)8-9-27-44(4)14-24(52)39(61)45(5,18-50)38(44)23(51)15-47(27,46)7)43(62)68-42-35(59)32(56)30(54)26(66-42)17-63-40-36(60)33(57)37(25(16-49)65-40)67-41-34(58)31(55)29(53)21(3)64-41/h8,19-21,23-42,49-61H,9-18H2,1-7H3/t19-,20+,21+,23-,24-,25-,26-,27-,28+,29+,30-,31-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42+,44-,45+,46-,47-,48+/m1/s1

InChI key: InChIKey=BNMGUJRJUUDLHW-HCZMHFOYSA-N

SMILES: C(O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)(=O)[C@]45[C@](C=6[C@@](C)(CC4)[C@@]7(C)[C@](CC6)([C@]8(C)[C@@]([C@H](O)C7)([C@@](CO)(C)[C@@H](O)[C@H](O)C8)[H])[H])([C@@H](C)[C@H](C)CC5)[H]

Synonyms:

• 6-deoxyhexopyranosyl-(1->4)hexopyranosyl-(1->6)-1-O-(2,3,6,23-tetrahydroxy-28-oxours-12-en-28-yl)hexopyranose
• Asiaticoside A
• Madecasoside
• Redermic
• Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, O-6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl-(1→4)-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-β-<smallcap>D</span>-glucopyranosyl ester, (2α,3β,4α,6β)-
• Madecassoside
• Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (2α,3β,4α,6β)-

[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-t

CAS: 34540-22-2

Formula: C₄₈H₇₈O₂₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 975.1209

Ref: IN-DA00I6TQ

Madecassoside

CAS: 34540-22-2

Formula: C₄₈H₇₈O₂₀

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 975.12

Ref: 7W-GC3156

Madecassoside

CAS: 34540-22-2

Formula: C₄₈H₇₈O₂₀

Molecular weight: 975.13

Ref: 4Z-M-276001

Madecassoside

CAS: 34540-22-2

Madecassoside is a mechanism-based inhibitor of CYP2C19 and CYP3A4, which has antioxidant, anti-inflammatory, anti-apoptosis, wound-healing, and neuroprotective activities, It may have cardioprotective effects in LPS-mediated through inhibition of ERK, p38, and NF-κB activity, it inhibited the pro-inflammatory mediators, including COX-2 expression, PGE2 production, TNF-αand IL-6 levels and the up-regulation anti-inflammatory molecule IL-10.

Formula: C₄₈H₇₈O₂₀

Purity: 95%~99%

Molecular weight: 975.132

Ref: BP-BP0911

Madecassoside

CAS: 34540-22-2

Madecassoside (Asiaticoside A) is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activities

Formula: C₄₈H₇₈O₂₀

Purity: 99.46% - 99.85%

Color and Shape: White Powder

Molecular weight: 975.12

Ref: TM-T2813

Madecassoside

CAS: 34540-22-2

Natural glycoside

Formula: C₄₈H₇₈O₂₀

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 975.14

Ref: 5G-80230

Madecassoside

CAS: 34540-22-2

Formula: C₄₈H₇₈O₂₀

Color and Shape: White Powder

Molecular weight: 975.12

Ref: TR-M107510

Asiaticoside A

CAS: 34540-22-2

Pentacyclic triterpene; anti-inflammatory, anti-oxidant & anti-ageing

Formula: C₄₈H₇₈O₂₀

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 975.12 g/mol

Ref: 3D-OM08291