CAS 345627-80-7

N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide

Description:

N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide, with CAS number 345627-80-7, is a synthetic organic compound characterized by its complex structure, which includes multiple functional groups such as thiazole, oxazole, and piperidine. This compound typically exhibits properties associated with its heterocyclic components, including potential biological activity. The presence of the thiazole and oxazole rings suggests it may interact with biological targets, making it of interest in medicinal chemistry. Additionally, the bulky 1,1-dimethylethyl group may influence its lipophilicity and solubility, affecting its pharmacokinetic properties. The compound is likely to be a solid at room temperature and may have specific melting and boiling points that are characteristic of similar organic compounds. Its synthesis and characterization would involve standard organic chemistry techniques, and it may be evaluated for its efficacy in various biological assays, particularly in the context of drug development.

Formula: C₁₇H₂₄N₄O₂S₂

InChI: InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)

InChI key: InChIKey=OUSFTKFNBAZUKL-UHFFFAOYSA-N

SMILES: C(SC=1SC(NC(=O)C2CCNCC2)=NC1)C=3OC(C(C)(C)C)=CN3

Synonyms:

• 4-Piperidinecarboxamide, N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-
• Bms 387032
• Bms-3870032
• Bms387032
• N-(5-(((5-(1,1-Dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-peridinecarboxamide
• N-(5-(((5-(1,1-Dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-piperidinecarboxamide
• N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide
• N-[5-[[(5-tert-Butyloxazol-2-yl)methyl]thio]thiazol-2-yl]piperidine-4-carboxamide
• Sns 032

SNS-032 (BMS-387032)

CAS: 345627-80-7

Formula: C₁₇H₂₄N₄O₂S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 380.5281

Ref: IN-DA00C6HP

N-(5-(((5-(Tert-Butyl)Oxazol-2-Yl)Methyl)Thio)Thiazol-2-Yl)Piperidine-4-Carboxamide

CAS: 345627-80-7

N-(5-(((5-(Tert-Butyl)Oxazol-2-Yl)Methyl)Thio)Thiazol-2-Yl)Piperidine-4-Carboxamide

Purity: 99%

Molecular weight: 380.53g/mol

Ref: 54-OR1024073

SNS-032

CAS: 345627-80-7

SNS-032

Purity: ≥98%

Molecular weight: 380.53g/mol

Ref: 54-BUP15421

SNS-032

CAS: 345627-80-7

Formula: C₁₇H₂₄N₄O₂S₂

Purity: >95.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 380.53

Ref: 3B-N1274

SNS-032

CAS: 345627-80-7

SNS-032 (BMS-387032) is a selective inhibitor of CDK2 and is 10- and 20-fold selective over CDK1/CDK4. SNS-032 is sensitive to CDK7/9, and no effect on CDK6.

Formula: C₁₇H₂₄N₄O₂S₂

Purity: 98.27% - 99.91%

Color and Shape: Solid

Molecular weight: 380.53

Ref: TM-T6049

SNS 032

CAS: 345627-80-7

Formula: C₁₇H₂₄N₄O₂S₂

Ref: TR-TRC-S590100

SNS 032

Controlled Product

CAS: 345627-80-7

Applications SNS 032 is a selective inhibitor of Cyclin-dependent Kinase (CDK) 2,7, and 9.
References Jones, C., et al.: Bioorg. Med. Chem. Lett., 18, 6486 (2008), Conroy, A., et al.: Canc. Chemother. Pharmacol., 64, 723 (2009), Ali, M., et al.: Int. J. Oncol., 34, 1051 (2009),

Formula: C₁₇H₂₄N₄O₂S₂

Color and Shape: Neat

Molecular weight: 380.53

Ref: TR-S590100

N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide

CAS: 345627-80-7

Formula: C₁₇H₂₄N₄O₂S₂

Purity: 99%

Color and Shape: Liquid, No data available.

Molecular weight: 380.53

Ref: 10-F240573

SNS 032

CAS: 345627-80-7

Inhibitor of cyclin-dependent kinases CDK2, CDK7 and CDK9

Formula: C₁₇H₂₄N₄O₂S₂

Purity: Min. 95%

Molecular weight: 380.53 g/mol

Ref: 3D-FS16408