CAS 3458-14-8

5'-deoxythymidine

Description:

5'-Deoxythymidine, also known as deoxythymidine or thymidine, is a nucleoside that plays a crucial role in the structure of DNA. It consists of a thymine base attached to a deoxyribose sugar, lacking a hydroxyl group at the 2' position, which distinguishes it from ribonucleosides. The chemical formula of 5'-deoxythymidine is C10H13N2O4, and it has a molecular weight of approximately 227.24 g/mol. This compound is essential for DNA synthesis and repair, as it serves as a building block for the formation of DNA strands. In biological systems, it is phosphorylated to form deoxythymidine monophosphate (dTMP), which can further be converted into deoxythymidine triphosphate (dTTP), a key substrate for DNA polymerases during DNA replication. 5'-Deoxythymidine is also used in various biochemical and pharmaceutical applications, including antiviral therapies and research involving nucleic acids. Its stability and solubility in aqueous solutions make it a valuable compound in molecular biology.

Formula: C₁₀H₁₄N₂O₄

InChI: InChI=1/C10H14N2O4/c1-5-4-12(10(15)11-9(5)14)8-3-7(13)6(2)16-8/h4,6-8,13H,3H2,1-2H3,(H,11,14,15)/t6-,7+,8-/m1/s1

Synonyms:

• 2',5'-Dideoxythymidine
• 5'-Ddthd
• Thymidine, 5'-deoxy-

5'-Deoxythymidine

CAS: 3458-14-8

Formula: C₁₀H₁₄N₂O₄

Purity: 98%

Molecular weight: 226.2292

Ref: IN-DA00C0Q1

5-deoxy Thymidine

CAS: 3458-14-8

5-deoxy Thymidine

Purity: ≥98%

Molecular weight: 226.23g/mol

Ref: 54-BUP05736

5''-Deoxythymidine

CAS: 3458-14-8

Ref: 7W-GN2612

5-deoxy Thymidine

CAS: 3458-14-8

5'-Deoxythymidine: a thymidine variant with hydrogen at the 5' position; combats Bacillus subtilis and Staphylococcus aureus.

Formula: C₁₀H₁₄N₂O₄

Purity: 99.72%

Color and Shape: Solid

Molecular weight: 226.23

Ref: TM-T21552

5'-Deoxythymidine

CAS: 3458-14-8

5'-Deoxythymidine is a nucleoside analog with low-energy electrons. This drug inhibits the synthesis of DNA by binding to the ribonucleotide reductase enzyme and preventing the conversion of ribonucleotides to deoxyribonucleotides. 5'-Deoxythymidine has been shown to inhibit cell growth in tumor cell lines, which may be due to its ability to interfere with mirna-mediated gene expression. This drug also has a kinetic effect on regulatory proteins, such as cyclin-dependent kinases, that are involved in the regulation of cell cycle progression.

Formula: C₁₀H₁₄N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 226.23 g/mol

Ref: 3D-ND08408