CAS 345909-25-3

2-amino-9-beta-D-ribofuranosyl-3,9-dihydro-6H-purine-6-thione hydrate

Description:

2-amino-9-beta-D-ribofuranosyl-3,9-dihydro-6H-purine-6-thione hydrate, with the CAS number 345909-25-3, is a purine derivative characterized by its ribofuranosyl moiety and a thiol group at the 6-position of the purine ring. This compound typically exhibits properties associated with nucleosides, including solubility in polar solvents due to the presence of hydroxyl groups. The amino group at the 2-position contributes to its potential biological activity, which may include roles in nucleic acid metabolism or as a precursor in biochemical pathways. The hydrate form indicates the presence of water molecules associated with the compound, which can influence its stability and solubility. As a purine analog, it may also exhibit interactions with enzymes or receptors involved in nucleic acid synthesis or regulation. Overall, this compound's structural features suggest potential applications in medicinal chemistry and biochemistry, particularly in the development of antiviral or anticancer agents.

Formula: C₁₀H₁₅N₅O₅S

InChI: InChI=1/C10H13N5O4S.H2O/c11-10-13-7-4(8(20)14-10)12-2-15(7)9-6(18)5(17)3(1-16)19-9;/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,20);1H2/t3-,5-,6-,9-;/m1./s1

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c2[nH]c(=N)nc3S)O1)O)O)O.O

6-Thioguanosine hydrate

CAS: 345909-25-3

Formula: C₁₀H₁₅N₅O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.3216

Ref: IN-DA00BY9G

2-Amino-9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-3,9-Dihydro-6H-Purine-6-Thione Hydrate

CAS: 345909-25-3

2-Amino-9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-3,9-Dihydro-6H-Purine-6-Thione Hydrate

Purity: 98%

Molecular weight: 317.32g/mol

Ref: 54-OR1027914

2-Amino-6-mercaptopurine-9-D-riboside Hydrate

CAS: 345909-25-3

Stability Hygroscopic
Applications 2-Amino-6-mercaptopurine-9-D-riboside Hydrate (cas# 345909-25-3) is a compound useful in organic synthesis.

Formula: C₁₀H₁₃N₅O₄S·x(H₂O)

Color and Shape: Light Yellow Powder

Molecular weight: 299.31

Ref: TR-A611850

Mercaptopurine Impurity 5

CAS: 345909-25-3

Formula: C₁₀H₁₃N₅O₄SH₂O

Molecular weight: 299.31 : 18.02

Ref: ST-EA-CP-M81012

2-Amino-6-mercaptopurine-9-D-riboside hydrate

CAS: 345909-25-3

2-Amino-6-mercaptopurine-9-D-riboside hydrate is a purine derivative that is used as a treatment for certain types of leukemia, such as acute lymphoblastic leukemia. It is converted to thioguanine in the body and inhibits the enzyme xanthine oxidase by forming hydrogen bonds with it. This prevents conversion of xanthine to uric acid, which results in an accumulation of uric acid in the blood. Thioguanine also inhibits the enzyme ribonucleotide reductase and reduces levels of nucleotides, which are needed for DNA synthesis. The drug has been shown to be effective when administered orally or intravenously. 2-Amino-6-mercaptopurine has been shown to possess antiinflammatory activities and can suppress immune reactions by inhibiting growth factor production by T cells. 2-Amino-6-mercaptopurine also binds to antibodies

Formula: C₁₀H₁₃N₅O₄S•(H₂O)x

Purity: Min. 97.5 Area-%

Molecular weight: 317.32 g/mol

Ref: 3D-VNA90925