CAS 346-55-4

4-Chloro-7-(trifluoromethyl)quinoline

Description:

4-Chloro-7-(trifluoromethyl)quinoline is an organic compound characterized by its quinoline structure, which consists of a fused benzene and pyridine ring. The presence of a chlorine atom at the 4-position and a trifluoromethyl group at the 7-position significantly influences its chemical properties and reactivity. This compound is typically a pale yellow to light brown solid, exhibiting moderate solubility in organic solvents such as ethanol and acetone, while being less soluble in water. Its molecular structure contributes to its potential applications in pharmaceuticals, agrochemicals, and as a building block in organic synthesis. The trifluoromethyl group enhances lipophilicity and can improve biological activity, making it of interest in medicinal chemistry. Additionally, 4-Chloro-7-(trifluoromethyl)quinoline may exhibit specific biological activities, including antimicrobial or antitumor properties, although detailed studies would be necessary to confirm these effects. As with many halogenated compounds, it is essential to handle this substance with care due to potential toxicity and environmental impact.

Formula: C₁₀H₅ClF₃N

InChI: InChI=1S/C10H5ClF3N/c11-8-3-4-15-9-5-6(10(12,13)14)1-2-7(8)9/h1-5H

InChI key: InChIKey=LLRQVSZVVAKRJA-UHFFFAOYSA-N

SMILES: ClC=1C2=C(C=C(C(F)(F)F)C=C2)N=CC1

Synonyms:

• 4-Chloro-7-trifluoromethylquinoline
• N-(tert-butoxycarbonyl)-2-(trifluoromethyl)phenylalanine
• Quinoline, 4-chloro-7-(trifluoromethyl)-
• 4-Chloro-7-(trifluoromethyl)quinoline
• 4-CHLORO-7-(TRIFLUOROMETHYL)QUINOLINE, 9 8%
• 4-Chloro-7-(trifluoromethyl)quinoline 98%
• BUTTPARK 15\09-27

4-Chloro-7-(Trifluoromethyl)Quinoline

CAS: 346-55-4

Formula: C₁₀H₅ClF₃N

Purity: 98%

Color and Shape: Solid

Molecular weight: 231.6016

Ref: IN-DA00BY8U

4-Chloro-7-(trifluoromethyl)quinoline

CAS: 346-55-4

4-Chloro-7-(trifluoromethyl)quinoline

Purity: 98%

Color and Shape: Tan Solid

Molecular weight: 231.60g/mol

Ref: 54-PC2075M

4-Chloro-7-(trifluoromethyl)quinoline

CAS: 346-55-4

Formula: C₁₀H₅ClF₃N

Purity: 98%

Color and Shape: Powder

Molecular weight: 231.6

Ref: 10-F004561

4-Chloro-7-(trifluoromethyl)quinoline

Controlled Product

CAS: 346-55-4

Applications 4-Chloro-7-(trifluoromethyl)quinoline is a reagent in the preparation of piperazinylquinolines as breast cancer inhibitors.
References Solomon, V., et al.: Bioorg. Med. Chem., 18, 1563 (2010);

Formula: C₁₀H₅ClF₃N

Color and Shape: Neat

Molecular weight: 231.6

Ref: TR-C422045