CAS 34604-60-9

5-Hydroxypyrazine-2-carboxylic acid

Description:

5-Hydroxypyrazine-2-carboxylic acid, with the CAS number 34604-60-9, is an organic compound characterized by its pyrazine ring structure, which is a six-membered aromatic ring containing two nitrogen atoms. This compound features a hydroxyl group (-OH) and a carboxylic acid group (-COOH) attached to the pyrazine ring, contributing to its polar nature and potential for hydrogen bonding. It is typically a white to off-white crystalline solid, soluble in water and various organic solvents, which enhances its utility in chemical reactions and formulations. The presence of both functional groups allows for diverse reactivity, making it a valuable intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Additionally, its biological activity may include antioxidant properties, although specific applications can vary. As with many organic compounds, handling should be done with care, following appropriate safety protocols to mitigate any potential hazards associated with its use.

Formula: C₅H₄N₂O₃

InChI: InChI=1S/C5H4N2O3/c8-4-2-6-3(1-7-4)5(9)10/h1-2H,(H,7,8)(H,9,10)

InChI key: InChIKey=CGQFCIHUUCMACC-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=CNC(=O)C=N1

Synonyms:

• 2-Pyrazinecarboxylic acid, 4,5-dihydro-5-oxo-
• 4,5-Dihydro-5-oxo-2-pyrazinecarboxylic acid
• 5-Hydropyrazine-2-Carboxylic Acid
• 5-Hydroxy-2-Pyrazinecarboxylic Acid
• 5-Hydroxy-Pyrazine-2-Carboxylic Acid
• 5-Hydroxypyrazine-2-Carboxylic Acid
• 5-Hydroxypyrazinoic Acid
• 5-Oxo-4,5-dihydropyrazine-2-carboxylic acid
• Pyrazinecarboxylic Acid, 4,5-Dihydro-5-Oxo-
• Pyrazinecarboxylic acid, 5-hydroxy-

5-Hydroxypyrazine-2-Carboxylic Acid

CAS: 34604-60-9

Formula: C₅H₄N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 140.0969

Ref: IN-DA00BZJ0

5-Hydroxypyrazine-2-Carboxylic Acid

CAS: 34604-60-9

5-Hydroxypyrazine-2-Carboxylic Acid is a metabolite of anti-tuberculosis drug pyrazinamide.

Formula: C₅H₄N₂O₃

Color and Shape: Brownish Powder

Molecular weight: 140.1

Ref: TM-T10171

5-Hydroxy-2-Pyrazinecarboxylic Acid

CAS: 34604-60-9

Formula: C₅H₄N₂O₃

Molecular weight: 140.10

Ref: 4Z-P-240003

5-Hydroxypyrazine-2-carboxylic acid

CAS: 34604-60-9

5-Hydroxypyrazine-2-carboxylic acid

Formula: C₅H₄N₂O₃

Purity: 97%

Color and Shape: dark brown solid

Molecular weight: 140.10g/mol

Ref: 54-OR40051

5-Hydroxypyrazine-2-carboxylic Acid

CAS: 34604-60-9

Applications A versatile building block for the synthesis of new antituberculous agents. A metabolite of Pyrazinamide (P840600).
References Wieser, M. et al.: Appl. Microbiol. Biotech., 48, 174 (1997); Lacroix, C. et al.: Eur. J. Clin. Pharmacol., 36, 395 (1989);

Formula: C₅H₄N₂O₃

Color and Shape: Light Yellow

Molecular weight: 140.10

Ref: TR-H952675

5-Hydroxypyrazine-2-carboxylic acid

CAS: 34604-60-9

Formula: C₅H₄N₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 140.098

Ref: 10-F037360

5-Hydroxypyrazine-2-carboxylic acid

CAS: 34604-60-9

5-Hydroxypyrazine-2-carboxylic acid is a drug that inhibits the activation of proteins involved in cell signaling pathways. It has been shown to have an inhibitory effect on the activation of protein kinase C, which plays a key role in the proliferation and differentiation of cells. 5-Hydroxypyrazine-2-carboxylic acid also inhibits sorafenib, a drug used for the treatment of cancer. Sorafenib is metabolized in rats by cytochrome P450 (CYP) enzymes, which are found in human liver tissue as well. The metabolism rate of sorafenib can be reduced by coadministration with caffeine or other substances that induce CYP activity. 5-Hydroxypyrazine-2-carboxylic acid is not active against pyrazinoic acid and pyrazine-2 carboxylate, which are metabolites produced by CYP enzymes.

Formula: C₅H₄N₂O₃

Purity: Min. 98 Area-%

Color and Shape: Brown Powder

Molecular weight: 140.1 g/mol

Ref: 3D-FH24492

5-Hydroxy-2-Pyrazinecarboxylic Acid-13C3

CAS: 34604-60-9

Formula: C₅H₄N₂O₃

Molecular weight: 143.07

Ref: 4Z-P-240004