CAS 34642-77-8

Amoxicillin Sodium

Description:

Amoxicillin sodium is a semi-synthetic antibiotic belonging to the penicillin group, primarily used to treat a variety of bacterial infections. It is characterized by its broad-spectrum activity against both Gram-positive and Gram-negative bacteria. The sodium salt form enhances its solubility in water, making it suitable for intravenous administration. Amoxicillin works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is generally well-absorbed when administered orally and has a favorable pharmacokinetic profile, allowing for effective dosing regimens. Commonly prescribed for respiratory tract infections, urinary tract infections, and skin infections, amoxicillin sodium is often combined with clavulanic acid to overcome bacterial resistance. Side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, more severe hypersensitivity reactions. Its safety profile makes it a widely used antibiotic in both pediatric and adult populations. As with all antibiotics, appropriate use is crucial to minimize the development of antibiotic resistance.

Formula: C₁₆H₁₉N₃NaO₅S

InChI: InChI=1/C16H19N3O5S.Na/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);/q;+1/p-1

InChI key: InChIKey=MAOIJBVJXINZLX-YWUHCJSESA-N

SMILES: C(O)(=O)[C@@H]1N2[C@@]([C@H](NC([C@H](N)C3=CC=C(O)C=C3)=O)C2=O)(SC1(C)C)[H].[Na]

Synonyms:

• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[2-amino-2-(p-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-, monosodium salt, (-)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1), (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-[2α,5α,6β(S*)]]-
• Amoxycillin sodium
• Amoxycillin sodium salt
• Amoxycilline Sodium
• Brl 2333Ab-B
• Na-6-[<span class="text-smallcaps">D</span>(-)-α-Amino-p-hydroxyphenylacetamido]penicillanic acid
• Sodium 6-{[Amino(4-Hydroxyphenyl)Acetyl]Amino}-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
• Sodium [2S-[2Alpha,5Alpha,6Beta(S*)]]-6-[[Amino(4-Hydroxyphenyl)Acetyl]Amino]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
• Sodium amoxicillin
• Sodium amoxycillin
• Sodium α-amino-p-hydroxybenzylpenicillin
• sodium (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• Na-6-[D(-)-α-Amino-p-hydroxyphenylacetamido]penicillanic acid
• AMOXICILLIN SODIUM
• amoxiclllln sodium
• (2S,5R,6R)-6-[[(R)-Amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt
• AmoxycillinSodiumSterileBp98
• (2S,5β)-6α-[[(R)-Amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid sodium salt

Amoxicillin sodium salt, 87% min.

CAS: 34642-77-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₆H₁₈N₃NaO₅S

Purity: 87%

Color and Shape: White to off-white, Powder or crystals or crystalline powder

Molecular weight: 387.39

Ref: 02-J66675

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt, (2S,5R,6R)-

CAS: 34642-77-8

Formula: C₁₆H₁₈N₃NaO₅S

Purity: 89%

Color and Shape: Liquid

Molecular weight: 387.3860

Ref: IN-DA00I6U9

Amoxicillin sodium salt

CAS: 34642-77-8

Formula: C₁₆H₁₈N₃NaO₅S

Purity: ≤ 3.0%

Color and Shape: White to almost white powder, very hygroscopic

Molecular weight: 387.39

Ref: 7W-GP0775

Amoxicillin Sodium

CAS: 34642-77-8

Amoxicillin Sodium

Purity: ≥98%

Molecular weight: 387.39g/mol

Ref: 54-BUP18896

Amoxicillin Sodium

CAS: 34642-77-8

Amoxicillin Sodium

Purity: 98%

Molecular weight: 387.39g/mol

Ref: 54-OR1029176

Amoxicillin Sodium

CAS: 34642-77-8

Amoxicillin Sodium (Clavulanate) is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.

Formula: C₁₆H₁₈N₃O₅S·Na

Purity: 98.45% - 99.2%

Color and Shape: White Or Almost White Crystalline Powder

Molecular weight: 387.39

Ref: TM-T6385

Amoxicillin sodium

CAS: 34642-77-8

Amoxicillin sodium is a penicillin antibiotic that inhibits bacterial cell wall synthesis. It is active against Gram-positive bacteria, such as Bacillus anthracis, Enterococcus faecalis, and Staphylococcus aureus. Amoxicillin sodium also inhibits the growth of Gram-negative bacteria, such as Salmonella typhi. It is used to treat a wide variety of infectious diseases caused by bacteria and protozoa, including respiratory tract infections, skin infections, urinary tract infections, gastrointestinal infections, ear infections, gonorrhea and syphilis. Amoxicillin sodium has been shown to have a good chemical stability in the presence of potassium ions and can be mixed with sulbactam or clavulanate potassium for enhanced efficacy in patients with high resistance to amoxicillin. The injection solution should be given intravenously with magnesium salt after glucose injection to increase blood levels of amoxicillin.

Formula: C₁₆H₁₈N₃NaO₅S

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 387.39 g/mol

Ref: 3D-FA37803

Amoxicillin sodium (Amox)

Controlled Product

CAS: 34642-77-8

Applications Amoxicillin sodium (Amox) (cas# 34642-77-8) is a useful research chemical.

Formula: C₁₆H₁₈N₃O₅S·Na

Color and Shape: White Powder

Molecular weight: 387.39

Ref: TR-A634548

Amoxicillin Dimer Sodium (>90%) (Mixture of Diastereomers)

CAS: 34642-77-8

Impurity Amoxicillin EP Impurity J
Applications Amoxicillin Dimer Sodium Salt is an impurity of Amoxicillin (A634235), a β-lactam family antibiotic that is commonly used in conjunction with clavulanic acid (C56370) to the treat bacterial infections.
References Gurwith, M., et al.: Antimicrob. Agents Ch., 24, 716 (1983); Kumar, A., et al.: J. Mater. Chem., 20, 10152 (2010);

Formula: C₃₂H₃₈N₆O₁₀S₂(xNa)

Purity: >90%

Color and Shape: Neat

Molecular weight: 730.81 (free acid)

Ref: TR-A634510