CAS 34642-77-8: Amoxicillin Sodium
Description:Amoxicillin sodium is a semi-synthetic antibiotic belonging to the penicillin group, primarily used to treat a variety of bacterial infections. It is characterized by its broad-spectrum activity against both Gram-positive and Gram-negative bacteria. The sodium salt form enhances its solubility in water, making it suitable for intravenous administration. Amoxicillin works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is generally well-absorbed when administered orally and has a favorable pharmacokinetic profile, allowing for effective dosing regimens. Commonly prescribed for respiratory tract infections, urinary tract infections, and skin infections, amoxicillin sodium is often combined with clavulanic acid to overcome bacterial resistance. Side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, more severe hypersensitivity reactions. Its safety profile makes it a widely used antibiotic in both pediatric and adult populations. As with all antibiotics, appropriate use is crucial to minimize the development of antibiotic resistance.
Formula:C16H18N3NaO5S
InChI:InChI=1S/C16H19N3O5S.Na/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);/t9-,10-,11+,14-;/m1./s1
InChI key:InChIKey=MAOIJBVJXINZLX-YWUHCJSESA-N
SMILES:[Na].O=C(O)C1N2C(=O)C(NC(=O)C(N)C3=CC=C(O)C=C3)C2SC1(C)C
- Synonyms:
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[2-amino-2-(p-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-, monosodium salt, (-)-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1), (2S,5R,6R)-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-[2α,5α,6β(S*)]]-
- Amoxycillin sodium
- Amoxycillin sodium salt
- Amoxycilline Sodium
- Brl 2333Ab-B
- Na-6-[<span class="text-smallcaps">D</span>(-)-α-Amino-p-hydroxyphenylacetamido]penicillanic acid
- Sodium 6-{[Amino(4-Hydroxyphenyl)Acetyl]Amino}-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
- See more synonyms
- Sodium [2S-[2Alpha,5Alpha,6Beta(S*)]]-6-[[Amino(4-Hydroxyphenyl)Acetyl]Amino]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
- Sodium amoxicillin
- Sodium amoxycillin
- Sodium α-amino-p-hydroxybenzylpenicillin
- sodium (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate