CAS 3466-81-7

Piperidine, 2-phenyl-, hydrochloride (1:1)

Description:

Piperidine, 2-phenyl-, hydrochloride (1:1), with the CAS number 3466-81-7, is a chemical compound that belongs to the class of piperidine derivatives. It features a piperidine ring, which is a six-membered saturated nitrogen-containing heterocycle, substituted with a phenyl group at the second position. As a hydrochloride salt, it is typically encountered in its protonated form, which enhances its solubility in water and makes it suitable for various applications in organic synthesis and medicinal chemistry. The compound exhibits basic properties due to the presence of the nitrogen atom in the piperidine ring, allowing it to act as a nucleophile in chemical reactions. Its structure may contribute to biological activity, making it of interest in pharmacological research. Safety data indicates that, like many piperidine derivatives, it should be handled with care due to potential irritant effects. Overall, Piperidine, 2-phenyl-, hydrochloride is a versatile compound with applications in both research and industry.

Formula: C₁₁H₁₅N·ClH

InChI: InChI=1S/C11H15N.ClH/c1-2-6-10(7-3-1)11-8-4-5-9-12-11;/h1-3,6-7,11-12H,4-5,8-9H2;1H

InChI key: InChIKey=YNQTWZUWWFUKSN-UHFFFAOYSA-N

SMILES: C1(=CC=CC=C1)C2CCCCN2.Cl

Synonyms:

• Piperidine, 2-phenyl-, hydrochloride
• 2-Phenylpiperidine hydrochloride
• Piperidine, 2-phenyl-, hydrochloride (1:1)

2-Phenylpiperidine hydrochloride

CAS: 3466-81-7

2-Phenylpiperidine hydrochloride

Purity: ≥95%

Molecular weight: 197.70g/mol

Ref: 54-OR13007

2-Phenylpiperidine hydrochloride

CAS: 3466-81-7

Purity: 95+%

Molecular weight: 197.7100067

Ref: 10-F652016

2-Phenylpiperidine hydrochloride

CAS: 3466-81-7

2-Phenylpiperidine hydrochloride is a diastereoselective, intramolecular reaction product of β-unsaturated ketones and piperidines. The synthesis of 2-phenylpiperidine hydrochloride involves a β-unsaturated ketone and two different piperidines. The reaction is intramolecular because the starting material is used in the same molecule as the reagent. This compound was shown to be a competitive inhibitor of serotonin transporter (SERT) with an IC 50 value of 0.8 μM.
Synlett, 2008, 2987-2989

Formula: C₁₁H₁₆ClN

Purity: Min. 95%

Molecular weight: 197.7 g/mol

Ref: 3D-DAA46681