CAS 346688-38-8

Pridopidine

Description:

Pridopidine, with the CAS number 346688-38-8, is a chemical compound that belongs to the class of compounds known as dopamine stabilizers. It is primarily investigated for its potential therapeutic effects in treating neurodegenerative disorders, particularly Huntington's disease. Pridopidine acts as a modulator of dopamine receptors, which helps to balance dopamine levels in the brain, potentially alleviating symptoms associated with dopamine dysregulation. The compound has shown promise in preclinical and clinical studies, demonstrating neuroprotective properties and the ability to improve motor function and cognitive performance in affected individuals. Its pharmacological profile suggests a unique mechanism of action that differentiates it from traditional dopaminergic therapies. Additionally, Pridopidine is characterized by its moderate lipophilicity, which may influence its bioavailability and distribution in the central nervous system. Ongoing research continues to explore its efficacy, safety, and optimal dosing regimens for various neurological conditions.

Formula: C₁₅H₂₃NO₂S

InChI: InChI=1S/C15H23NO2S/c1-3-9-16-10-7-13(8-11-16)14-5-4-6-15(12-14)19(2,17)18/h4-6,12-13H,3,7-11H2,1-2H3

InChI key: InChIKey=YGKUEOZJFIXDGI-UHFFFAOYSA-N

SMILES: S(C)(=O)(=O)C=1C=C(C=CC1)C2CCN(CCC)CC2

Synonyms:

• Piperidine, 4-[3-(methylsulfonyl)phenyl]-1-propyl-
• ACR 16
• ASP 2314
• Pridopidine
• 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine

4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine

CAS: 346688-38-8

Formula: C₁₅H₂₃NO₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 281.4136

Ref: IN-DA00C9G6

Pridopidine

CAS: 346688-38-8

Pridopidine

Purity: ≥95%

Molecular weight: 281.41g/mol

Ref: 54-BUP16259

Pridopidine

CAS: 346688-38-8

Pridopidine (FR310826), a low-affinity D2R antagonist, enhances motor skills and has neuroprotective effects in Huntington's R6/2 mice.

Formula: C₁₅H₂₃NO₂S

Purity: 95.2% - 99.89%

Color and Shape: Solid

Molecular weight: 281.41

Ref: TM-T7352

4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine

CAS: 346688-38-8

4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine is a low-potency, selective inhibitor of cytochrome P450 (CYP). It has been shown to inhibit p450 activity in rat and human liver microsomes. 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine is also a neuroprotectant that restores mitochondrial function and protects against the degenerative effects of dopamine. This drug decreases locomotor activity in rats and has been used as an anthelmintic drug. 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine is metabolized by CYP enzymes and may have other pharmacological activities due to its ability to inhibit CYPs.

Formula: C₁₅H₂₃NO₂S

Purity: Min. 95%

Color and Shape: White to off-white solid.

Molecular weight: 281.41 g/mol

Ref: 3D-FM25954

4-(3-(Methylsulfonyl)phenyl)-1-propylpiperidine

CAS: 346688-38-8

Formula: C₁₅H₂₃NO₂S

Purity: 95%

Color and Shape: No data available.

Molecular weight: 281.41

Ref: 10-F334938

4-(3-Methylsulfonylphenyl)-1-propylpiperidine

Controlled Product

CAS: 346688-38-8

Applications A new modulator of dopamine neurotransmission. Dopamine is a neurotransmitter in the brain. Drugs that act at central dopamine receptors are commonly used in the treatment of neurologic and psychiatric disorders.
References Eidelberg, D., et al.: Brain, 120, 1315 (1997), Feigin, A., et al.: J. Nucl. Med., 42, 1591 (2001), Walker, F., et al.: Lancet, 369, 218 (2007), Dyhring, T., et al.: Eur. J. Pharmacol., 628, 19 (2010),

Formula: C₁₅H₂₃NO₂S

Color and Shape: Neat

Molecular weight: 281.41

Ref: TR-M326195

4-(3-Methylsulfonylphenyl)-1-propylpiperidine

CAS: 346688-38-8

Formula: C₁₅H₂₃NO₂S

Molecular weight: 281.41

Ref: ST-EA-CP-D55026