CAS 346735-24-8: Amelubant

Description:Amelubant, identified by the CAS number 346735-24-8, is a chemical compound that has garnered attention in pharmaceutical research, particularly for its potential therapeutic applications. It is classified as a selective antagonist of the chemokine receptor CCR2, which plays a significant role in inflammatory processes and immune responses. The compound's mechanism of action involves inhibiting the binding of chemokines to CCR2, thereby modulating inflammatory pathways. This characteristic makes Amelubant a candidate for treating conditions associated with chronic inflammation, such as certain autoimmune diseases and cardiovascular disorders. In terms of physical properties, specific details such as solubility, melting point, and stability may vary and are typically determined through experimental studies. As with many pharmaceutical compounds, safety and efficacy are evaluated through clinical trials to establish appropriate dosing and potential side effects. Overall, Amelubant represents a promising area of research in the development of targeted therapies for inflammatory diseases.

Formula:C₃₃H₃₄N₂O₅

InChI:InChI=1S/C33H34N2O5/c1-4-38-32(37)35-31(34)25-8-16-29(17-9-25)39-21-23-6-5-7-24(20-23)22-40-30-18-12-27(13-19-30)33(2,3)26-10-14-28(36)15-11-26/h5-20,36H,4,21-22H2,1-3H3,(H2,34,35,37)

InChI key:InChIKey=SBVYURPQULDJTI-UHFFFAOYSA-N

SMILES:O=C(OCC)NC(=N)C1=CC=C(OCC2=CC=CC(=C2)COC3=CC=C(C=C3)C(C4=CC=C(O)C=C4)(C)C)C=C1

Synonyms:
Amelubant
Biil-284
Carbamic acid, N-[[4-[[3-[[4-[1-(4-hydroxyphenyl)-1-methylethyl]phenoxy]methyl]phenyl]methoxy]phenyl]iminomethyl]-, ethyl ester
Carbamic acid, [[4-[[3-[[4-[1-(4-hydroxyphenyl)-1-methylethyl]phenoxy]methyl]phenyl]methoxy]phenyl]iminomethyl]-, ethyl ester
ethyl {(E)-[(4-{[3-({4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy}methyl)benzyl]oxy}phenyl)amino]methylidene}carbamate - ethane (1:1)

Found 2 products.

Brand	Product data	Purity	Price range	Estimated delivery
	Amelubant REF: TM-T14210CAS: 346735-24-8	98%	To inquire	Mon 05 May 25
	Amelubant REF: 3D-WNA73524CAS: 346735-24-8	Min. 95%	525.00 €~4,453.00 €	Tue 17 Jun 25