CAS 3469-69-0

4-Iodopyrazole

Description:

4-Iodopyrazole is a heterocyclic organic compound characterized by the presence of a pyrazole ring substituted with an iodine atom at the 4-position. Its molecular formula is C3H3I N2, indicating that it contains three carbon atoms, three hydrogen atoms, one iodine atom, and two nitrogen atoms. This compound typically appears as a solid and is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its ability to interact with biological targets. The presence of the iodine atom can enhance the compound's lipophilicity and influence its biological activity. 4-Iodopyrazole can be synthesized through various methods, including halogenation of pyrazole derivatives. It is important to handle this compound with care, as iodine can be hazardous, and appropriate safety measures should be taken during its use and storage. Additionally, its reactivity can be exploited in further chemical transformations, making it a valuable intermediate in organic synthesis.

Formula: C₃H₃IN₂

InChI: InChI=1S/C3H3IN2/c4-3-1-5-6-2-3/h1-2H,(H,5,6)

InChI key: InChIKey=LLNQWPTUJJYTTE-UHFFFAOYSA-N

SMILES: IC=1C=NNC1

Synonyms:

• 1-Iodopyrazole
• 1H-Pyrazole, 4-iodo-
• 4-Iodo pyrazole
• 4-Iodophrazole
• 4-iodo-1H-pyrazole
• Iodopyrazole, 4-
• Pyrazole, 4-iodo-
• 4-Iodo-1H-pyrazol
• 4-Iodopyrazole

4-Iodopyrazole

CAS: 3469-69-0

Formula: C₃H₃IN₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 193.98

Ref: 3B-I0692

4-Iodo-1H-pyrazole, 99%

CAS: 3469-69-0

4-Iodopyrazole was used in an indium-mediated synthesis of heterobiaryls. It undergoes iodination in the presence of iodine and ammonium hydroxide to yield 3,4-di-iodo- and 3,4,5-tri-iodo-pyrazole. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio

Formula: C₃H₃IN₂

Purity: 99%

Molecular weight: 193.98

Ref: 02-H56369

4-Iodopyrazole

CAS: 3469-69-0

Formula: C₃H₃IN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 193.9738

Ref: IN-DA003LKY

4-Iodo-1H-pyrazole

CAS: 3469-69-0

4-Iodo-1H-pyrazole

Formula: C₃H₃IN₂

Purity: 99%

Color and Shape: white to off-white powder

Molecular weight: 193.97g/mol

Ref: 54-OR10990

4-Iodopyrazole

CAS: 3469-69-0

Purity: 98%

Molecular weight: 193.974

Ref: FT-Y15229

4-Iodopyrazole

CAS: 3469-69-0

Formula: C₃H₃IN₂

Purity: 98%

Color and Shape: Chunks,Crystalline Powder,Flakes,Powder

Molecular weight: 193.975

Ref: 10-F005458

4-Iodopyrazole

Controlled Product

CAS: 3469-69-0

Applications 4-Iodopyrazole is used in the synthesis of (pyrazolyl)oxobenzocycloheptapyridinyl acetamides that act as inhibitors of c-Met.
References Northrup, A. et al.: J. Med. Chem., 56, 2294 (2013);

Formula: C₃H₃IN₂

Color and Shape: Neat

Molecular weight: 193.97

Ref: TR-I719470