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CAS 347146-22-9

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8-(Trifluoromethyl)-3-quinolinamine

Description:
8-(Trifluoromethyl)-3-quinolinamine is a chemical compound characterized by its quinoline structure, which consists of a bicyclic aromatic system containing a nitrogen atom. The presence of a trifluoromethyl group (-CF3) at the 8-position significantly influences its chemical properties, enhancing lipophilicity and potentially affecting its biological activity. The amino group (-NH2) at the 3-position contributes to its basicity and can participate in hydrogen bonding, making it a versatile building block in medicinal chemistry. This compound may exhibit interesting pharmacological properties, including potential applications in drug development, particularly in targeting specific biological pathways. Its unique structure allows for various synthetic modifications, which can lead to derivatives with enhanced efficacy or selectivity. Additionally, the trifluoromethyl group is known to improve metabolic stability and bioavailability. As with many quinoline derivatives, 8-(Trifluoromethyl)-3-quinolinamine may also display fluorescence properties, making it useful in analytical applications. Overall, this compound represents a valuable entity in the field of organic and medicinal chemistry.
Formula:C10H7F3N2
InChI:InChI=1S/C10H7F3N2/c11-10(12,13)8-3-1-2-6-4-7(14)5-15-9(6)8/h1-5H,14H2
InChI key:InChIKey=QGMUHKAEGCPBLW-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C=1C2=C(C=C(N)C=N2)C=CC1
Synonyms:
  • 3-Quinolinamine, 8-(trifluoromethyl)-
  • 8-(Trifluoromethyl)-3-quinolinamine
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